Papers -
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ポリイミド基板上への選択的金属有機構造体の形成技術 Reviewed
福岡美海、江口慧一、髙嶋洋平、赤松謙祐、鶴岡孝章
ポリイミドの高機能設計と応用技術 6 ( 6 ) 487 - 495 2022
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Cooperative catalysis in a metal–organic framework <i>via</i> post-synthetic immobilisation Reviewed
Yohei Takashima, Yuya Suwaki, Takaaki Tsuruoka, Kensuke Akamatsu
Dalton Transactions 51 ( 24 ) 9229 - 9232 2022
Publisher：Royal Society of Chemistry (RSC)
A Co-salen complex and a MOF were successfully hybridized by post-synthetic immobilization for a cooperative catalytic system.
DOI： 10.1039/d2dt01544g
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Rational and site-selective formation of coordination polymers consisting of d<sup>10</sup> coinage metal ions with thiolate ligands using a metal ion-doped polymer substrate Reviewed International coauthorship
Takaaki Tsuruoka, Yuri Miyashita, Ryuki Yoshino, Myu Fukuoka, Shoya Hirao, Yohei Takashima, Aude Demessence, Kensuke Akamatsu
RSC Advances 12 ( 6 ) 3716 - 3720 2022
Authorship：Lead author, Corresponding author Publisher：Royal Society of Chemistry (RSC)
We report an interfacial approach for fabricating coordination polymer (CP) crystal films and patterns on a polymer surface using a metal ion-doped polymer substrate.
DOI： 10.1039/d2ra00269h
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ポリイミド基板上への選択的金属有機構造体の形成技術
福岡美海、江口慧一、髙嶋洋平、赤松謙祐、鶴岡孝章
ポリイミドの高機能設計と応用技術 6 ( 6 ) 487 - 495 2022
Authorship：Corresponding author
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Rational and site-selective formation of coordination polymer consisiting of d10 coinage metal ions with thiolate ligands using metal ion-doped polymer substrate Reviewed International coauthorship
T. Tsuruoka, Y. Miyashita, R. Yoshino, M. Fukuoka, S. Hirao, Y. Takashima, A. Demessence, K. Akamatsu
RSC Adv 12 3716 - 3720 2022
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Intramolecular G-Quadruplex-Hairpin Loop Structure Competition of a GC-Rich Exon Region in the TMPRSS2 Gene. Reviewed
Sugimoto W, Kinoshita N, Nakata M, Ohyama T, Tateishi-Karimata H, Nishikata T, Sugimoto N, Miyoshi D, Kawauchi K
Chem Commun (Camb) 58 ( 1 ) 48 - 51 2021.12
Joint Work
DOI： 10.1039/d1cc05523b
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Anti-Malignant Effect of Tensile Loading to Adherens Junctions in Cutaneous Squamous Cell Carcinoma Cells Reviewed International journal
Dobrokhotov O, Sunagawa M, Torii T, Mii S, Kawauch K, Enomoto A, Sokabe M, Hirata H.
Frontiers in Cell and Developmental Biology 11 2021.11
Joint Work
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Injectable Biocatalytic Nanocomposite Hydrogel Factories for Focal Enzyme-Prodrug Cancer Therapy Reviewed
Kimika Ono, Hiroyuki Hashimoto, Tokitaka Katayama, Natsumi Ueda, Koji Nagahama
Biomacromolecules 22 ( 10 ) 4217 - 4227 2021.10
Authorship：Last author, Corresponding author
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Supercapacitor electrode with high charge density based on boron-doped porous carbon derived from covalent organic frameworks Reviewed
Shigeyuki Umezawa, Takashi Douura, Koji Yoshikawa, Yohei Takashima, Mika Yoneda, Kazuma Gotoh, Vlad Stolojan, S. Ravi P. Silva, Yasuhiko Hayashi, Daisuke Tanaka
Carbon 184 418 - 425 2021.10
Publisher：Elsevier BV
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Koji Nagahama, Seika Aoyama, Natsumi Ueda, Yuka Kimura, Tokitaka Katayama, Kimika Ono
ACS Macro Letters 10 ( 8 ) 1073 - 1079 2021.8
Authorship：Lead author, Corresponding author
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Involvement of Annexin A2 in Serum-MAF Dependent Phagocytic Activation of Macrophages. Reviewed
Kawakatsu K, Seta Y, Maemura M, Nishikata T.
Anticancer Research 41 ( 8 ) 4089 - 4092 2021.8
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ウォッシャーディスインフェクターのすすぎ排水中に含まれる洗浄剤残留量の測定によるすすぎ性能評価 Reviewed
三軒隼人、藤田敏、川田原瑠勇、武川公、臼井健二、原田陽滋
医療機器学 91 315 - 332 2021.8
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Enhancement of the Catalytic Activity of Hammerhead Ribozymes by Organic Cations. Reviewed International journal
Shu-Ichi Nakano, Hirofumi Yamashita, Naoki Sugimoto
ChemBioChem 22 ( 17 ) 2721 - 2728 2021.7
Joint Work
Authorship：Lead author, Corresponding author
Catalytic turnover is important for the application of ribozymes to biotechnology. However, the turnover is often impaired because of the intrinsic high stability of base pairs with cleaved RNA products. Here, organic cations were used as additives to improve the catalytic performance of hammerhead ribozyme constructs that exhibit different kinetic behaviors. Kinetic analysis of substrate cleavage demonstrated that bulky cations, specifically tetra-substituted ammonium ions containing pentyl groups or a benzyl group, have the ability to greatly increase the turnover rate of the ribozymes. Thermal stability analysis of RNA structures revealed that the bulky cations promote the dissociation of cleaved products and refolding of incorrectly folded structures with small disruption of the catalytic structure. The use of bulky cations is a convenient method for enhancing the catalytic activity of hammerhead ribozymes, and the approach may be useful for advancing ribozyme technologies.
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Zayed, M., Iohara, K., Watanabe, H., Ishikawa, M., Tominaga, M. and Nakashima, M.
Stem Cell Res Ther. 12 ( 302 ) 2021.5
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Detection of Intracellular Reactive Oxidative Species Using the Fluorescent Probe Hydroxyphenyl Fluorescein Invited Reviewed
Wataru Sugimoto, Daisuke Miyoshi, Keiko Kawauchi
Methods in Molecular Biology 2274 207 - 215 2021.5
Publisher：Humana Press Inc.
Various fluorescent probes for the detection of intracellular reactive oxidative species (ROS) have been developed because ROS levels are closely associated with cellular states. Here, we describe a method for detection of intracellular ROS in living cells using the fluorescent probe, hydroxyphenyl fluorescein (HPF), which detects hydroxyl radicals and peroxynitrite. NIH3T3 cells and p53 knockout (p53−/−) mouse embryonic fibroblasts (MEFs) were transformed by expressing oncogenic RAS using a retrovirus system. The cells were treated with HPF at 37 °C for 30 min, and subsequently, images were acquired using a confocal fluorescence microscope at an excitation wavelength of 488 nm after washing with PBS.
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Molecularly targeted photodynamic therapy for cancer mRNAs Invited Reviewed
杉本渉, 橋本佳樹, 川内敬子, 三好大輔
Bio Clinica 36 ( 5 ) 65 - 67 2021.5
Joint Work
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Controlling interfacial ion-transport kinetics using polyelectrolyte membranes for additive- and effluent-free, high-performance electrodeposition Reviewed International journal
K. Akamatsu, S. Nakano, K. Kimura, Y. Takashima, T. Tsuruoka, H. Nawafune, Y. Sato, J. Murai, and H. Yanagimoto
ACS Appl. Mater. Interfaces 13 ( 11 ) 13896 - 13906 2021.3
Joint Work
Publisher：ACS Publications
The development of high-performance, environmentally friendly electrodeposition processes is critical for emerging coating technologies because current technologies use highly complex baths containing metal salts, supporting electrolytes, and various kinds of organic additives, which are problematic from both environmental and cost perspectives. Here, we show that a 200 μm-thin polyelectrolyte membrane sandwiched between electrodes effectively concentrates metal ions through interfacial penetration, which increases the conductance between the electrodes to 0.30 S and realizes solid-state electrodeposition that produces no mist, sludge, or even waste effluent. Both, experimental results and theoretical calculations, reveal that electrodeposition is controlled by ion penetration at the solution/polyelectrolyte interface, providing an intrinsically different ion-transport mechanism to that of conventional diffusion-controlled electrodeposition. The setup, which includes 0.50 mol L–1 copper sulfate and no additives, delivers a maximum current density of 300 mA cm–2, which is nearly fivefold higher than that of a current commercial plating bath containing organic additives.
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核小体ストレスにより形成するrDNA G-quadruplex集合体とその機能
杉本 渉, 桑本 慎, 建石 寿枝, 岩根 敦子, 高橋 宏隆, 三好 大輔, 川内 敬子
日本薬学会年会要旨集 141年会 29V05 - am10S 2021.3
Publisher：(公社)日本薬学会
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Covalent cell-loading injectable hydrogel scaffold significantly promotes tissue regeneration in vivo compared with a conventional physical cell-loading hydrogel scaffold Reviewed
Yuka Kimura, Seika Aoyama, Natsumi Ueda, Tokitaka Katayama, Kimika Ono, Koji Nagahama
Advanced Biology 5 2000106 2021.2
Joint Work
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Hydrostatic Pressure-Regulated Cellular Calcium Responses. Reviewed International journal
Minami Fukuchi, Kotaro Oyama, Hiroaki Mizuno, Akihisa Miyagawa, Kazuya Koumoto, Gaku Fukuhara
Langmuir : the ACS journal of surfaces and colloids 37 ( 2 ) 820 - 826 2021.1
Joint Work
Hydrostatic pressure control has attracted much attention and presents a still challenging objective from mechanobiological viewpoints. Herein, we reveal the calcium entry processes in HeLa cells by means of hydrostatic pressure spectroscopy. The steady-state fluorescence spectral data comprehensively elucidated the factors controlling the outcomes of the hydrostatic pressure-stimulated calcium entry behavior. The present work leads to a new perspective on ion regulations in living cells and an attractive alternative to conventional mechanostimuli.