Papers -
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MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility. Reviewed
Hirata H, Ku WC, Yip AK, Ursekar CP, Kawauchi K, Roy A, Guo AK, Vedula SR, Harada I, Chiam KH, Ishihama Y, Lim CT, Sawada Y, Sokabe M
Journal of Cell Science 129 ( 19 ) 3574 - 3582 2016.10
Joint Work
DOI： 10.1242/jcs.189415
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A Systematic Study on Molecular Mechanism of Pore-Forming Peptides for Discovering Antimicrobial Medicine
Y. Sekiya, H. Watanabe, K. Usui, R. Kawano
Proceedings of MicroTAS 2016 595 - 596 2016.10
Joint Work
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Increased yield of beta-glucosidase-catalyzed hydrolysis reactions in the presence of betaine-type metabolite analog Reviewed International journal
Shiro Sehata, Ryojun Suzuki, Kazuya Koumoto
BIOPROCESS AND BIOSYSTEMS ENGINEERING 40 ( 1 ) 153 - 159 2016.9
Joint Work
Publisher：SPRINGER
beta-Glucosidases (EC 3.2.1.21), abundant enzymes distributed in animals, plants and microorganism, has been generating lots of attentions for bioethanol production from cellulosic biomass. In this study, using three different origins of beta-glucosidases, glucose productivity of beta-glucosidase-catalyzed hydrolysis reactions in the presence of synthetic betaine-type metabolite analog (2-N,N,N-tri-n-butylammonium) acetate, was investigated. By the addition of the analog, the hydrolysis yields for all beta-glucosidases was highly improved from 4-13 to 64-100 %. To understand the factors affecting on the yield enhancements, the kinetic parameters, inhibition constants of end-product and temporal stability of beta-glucosidases were compared. As a result, enhancement of the yields is mainly related to the increase in the temporal stability of beta-glucosidases in the presence of the analog. The present findings lead to not only improve the glucose productivity of beta-glucosidase-catalyzed hydrolysis reaction toward bioethanol production but also apply to a new stabilization method for various unstable enzymes.
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Local thermodynamics of the water molecules around single- and double-stranded DNA studied by grid inhomogeneous solvation theory Reviewed
M. Nakano, H. Tateishi-Karimata, S. Tanaka, F. Tamab, O. Miyashita, S. Nakano, and N. Sugimoto
Chem. Phys. Lett. 660 ( 1 ) 250 - 255 2016.9
Joint Work
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Discovery of a new function of curcumin which enhances its anticancer therapeutic potency Reviewed
Koji Nagahama, Tomoya Utsumi, Takayuki Kumano, Saeko Maekawa, Naho Oyama, Junji Kawakami
Scientific Reports 6 30962 2016.8
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Curcumisome nanovesicles generated by self-assembly of curcumin amphiphiles toward cancer theranostics Reviewed
K. Nagahama, T. Utsumi, T. Kumano, S. Maekawa, N. Oyama, J. Kawakami
Scientific Reports 6 30962 2016.8
Joint Work
Authorship：Lead author
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Macrophages Exhibit a Large Repertoire of Activation States via Multiple Mechanisms of Macrophage-activating Factors. Reviewed
Sumiya Y.U., Inoue T., Ishikawa M., Inui T., Kuchiike D., Kubo K., Uto Y., Nishikata T.
Anticancer Res. 36 ( 7 ) 3619 - 3623 2016.7
Joint Work
Authorship：Lead author
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Case Report: GcMAF Treatment in a Patient with Multiple Sclerosis. Reviewed
Inui T., Katsuura G., Kubo K., Kuchiike D., Chenery L., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3771 - 3774 2016.7
Joint Work
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Case Report: A Non-small Cell Lung Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Tumor Treating Fields. Reviewed
Inui T., Amitani H., Kubo K., Kuchiike D., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3767 - 6770 2016.7
Joint Work
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Use of a ureido-substituted deoxycytidine module for DNA assemblies Invited Reviewed
S. Nakano, H. Oka, M. Fujii, and N. Sugimoto
Nucleosides, Nucleotides and Nucleic Acids 35 ( 7 ) 370 - 378 2016.5
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A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers Invited Reviewed
M. Yamaguchi, Y. Zouzumi, N. Shimada, S. Nakano, N. Sugimoto, A. Maruyama, and D. Miyoshi
Chem. Commun. 52 7446 - 7449 2016.4
Joint Work
DOI： 10.1039/C6CC02237E
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Site-Specific Control of Silica Mineralization on DNA Using a Designed Peptide Reviewed
M. Ozaki, K. Nagai, H. Nishiyama, T. Tsuruoka, S. Fujii, T. Endoh, T. Imai, K.-y. Tomizaki, K. Usui
Chem. Commun. 52 4010 - 4013 2016.3
Joint Work
Authorship：Lead author
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Site-specific control of silica mineralization on DNA using a designed peptide Reviewed
Makoto Ozaki, Kazuma Nagai, Hiroto Nishiyama, Takaaki Tsuruoka, Satoshi Fujii, Tamaki Endoh, Takahito Imai, Kin-ya Tomizaki, Kenji Usui
Chemical Communications 52 ( 21 ) 4010 - 4013 2016.3
Joint Work
DOI： 10.1039/C5CC07870A
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Development of Designed Peptides with Secondary Structure for Use in Nanobiotechnology Invited Reviewed
K.Usui
Peptide Science 2015 5 - 8 2016.3
Single Work
Authorship：Lead author
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The structural stability and catalytic activity of DNA and RNA oligonucleotides in the presence of organic solvents Invited Reviewed
S. Nakano and N. Sugimoto
Biophys. Rev. 8 ( 1 ) 11 - 23 2016.1
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Reevaluation of the stability of G-quadruplex structures under crowding conditions Reviewed
Jun Zhou, Hisae Tateishi-Karimata, Jean-Louis Mergny, Mingpan Cheng, Zhaochi Feng, Daisuke Miyoshi, Naoki Sugimoto, Can Li
Biochimie 121 204 - 208 2016
Joint Work
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A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers Reviewed
Nonoka Yamaguchi, Yu-ki Zouzumi, Naohiko Shimada, Shuichi Nakano, Naoki Sugimoto, Atsushi Maruyama, Daisuke Miyoshi
Chem. Commun. 52 7446 - 7449 2016
Joint Work
Authorship：Lead author
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In situ synthesis of Cu/Ni alloy nanoparticles embedded in thin polymer layers Reviewed
R. Shimizu, T. Kawakami, Y. Takashima, T. Tsuruoka, K. Akamatsu
RSC Adv 6 18895 - 18898 2016
Joint Work
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Morphology Control of Metal-Organic Frameworks Based on Paddle-Wheel Units on Ion-Doped Polymer Substrate Using An Interfacial Growth Approach Reviewed
T. Tsuruoka*, K. Mantani, A. Miyanaga, T. Matsuyama, T. Ohhashi, Y. Takashima, K. Akamatsu
Langmuir 32 6068 - 6073 2016
Joint Work
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Interfacial Synthetic Approach for Constructing Metal-Organic Framework Crystals Using Metal Ion-Doped Polymer Substrate Reviewed
T. Tsuruoka*, M. Kumano, K. Mantani, T. Matsuyama, A. Miyanaga, T. Ohhashi, Y. Takashima, H. Minami, T. Suzuki, K. Imagawa, K. Akamatsu
Cryst. Growth Des 16 2472 - 2476 2016
Joint Work