Papers -
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Structure-function relationship of a histidine dependent ribozyme
Y. Yamaguchi, Y. Ishibashi, S. Tanaka, A. Tanigawa, I. Matsunaga, and J. Kawakami
Proc. 38th Intl. Symp. Nucleic Acids Chemistry 194 - 195 2011.11
Joint Work
Authorship：Lead author
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Cell fingerprint patterns using designed alpha-helical peptides to screen for cell-specific toxicity Reviewed
Kenji Usui, Takashi Kakiyama, Kin-ya Tomizaki, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 21 ( 21 ) 6281 - 6284 2011.11
Publisher：PERGAMON-ELSEVIER SCIENCE LTD
We conducted cell-based cytotoxicity screening of a 101-membered alpha-helical peptide library using cell fingerprints (CFPs). The CFP data suggested that there is a relationship between cytotoxicity and peptide characteristics, such as hydrophobicity, charge, and amino acid composition. In spite of the small size of the library used in this study, several peptides demonstrated cell-specific toxicity. The strategy of combining a designed peptide library with CFP thus shows real promise for peptide-based screening with cells. (C) 2011 Elsevier Ltd. All rights reserved.
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Triplet analysis that identifies unpaired regions of functional RNAs（共著） Reviewed
J. Kawakami, Y. Yamaguchi, and N. Sugimoto
Journal of Nucleic Acids 2011 doi:10.4061/2011/471843 2011.10
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The effects of molecular crowding on the structure and stability of G-quadruplexes with an abasic site Invited Reviewed
T. Fujimoto, S. Nakano, D. Miyoshi, and N. Sugimoto
Journal of Nucleic Acids (Hindawl Publishing Corporation) 2011 ( 857149 ) 857149 2011.9
Joint Work
DOI： 10.4061/2011/857149
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A Novel Nitric Oxide Sensor Using Fluorescenct Peptides Attached to Iron Complexes
Hiroshi Miyazaki, Kenji Usui, Satoshi Fujii
Peptides: Building Bridges. Proceeding of the Twenty-Second American Peptide Symposium 224 - 225 2011.9
Joint Work
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Graphene biosensors Invited
D. Miyoshi, N. Sugimoto
Chemistry 66 ( 8 ) 30 - 35 2011.9
Joint Work
Authorship：Lead author
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The effects of molecular crowding on the structure and stability of G-quadruplexes with an abasic site Reviewed
Takeshi Fujimoto, Shu Ichi Nakano, Daisuke Miyoshi, and Naoki Sugimoto
J. Nucleic Acids 2011 857149 2011.9
Joint Work
Authorship：Lead author
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Graphene biosensors
D. Miyoshi, N. Sugimoto
Chemistry 66 ( 8 ) 30 - 35 2011.9
Joint Work
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Fabrication of Silver Patterns on Polyimide Films Based on Solid-Phase Electrochemical Constructive Lithography Using Ion-Exchangeable Precursor Layers
K. Akamatsu, Y. Fukumoto, T. Taniyama, T. Tsuruoka, H. Yanagimoto, H. Nawafune
Langmuir 27 11761 - 11766 2011.9
Joint Work
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Contlloed Self-Assembly of Metal-Organic Frameworks on Metal Nanoparticles for Efficient Synthesis of Hybrid Nanostructures
T. Tsuruoka, H. Kawasaki, H. Nawafune, K. Akamatsu
Contlloed Self-Assembly of Metal-Organic Frameworks on Metal Nanoparticles for Efficient Synthesis of Hybrid Nanostructures 3 3788 - 3791 2011.9
Joint Work
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Contlloed Self-Assembly of Metaｌ-Organic Frameworks on Metal Nanoparticle for Efficient Synthesis of Hybrid Nanostructures Reviewed
T.Tsuruoka, H.Kawasaki, H. Nawafune, K. Akamatsu
ACS Appl. Mater. Interfaces 3 3788 - 3791 2011.9
Joint Work
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Fabrication of Silver Patterns on Polyimide Films Based on Solid-Phase Electrochemical Constructive Lithography Using Ion-Exchangeable Precursor Layers
K. Akamatsu, Y. Fukumoto, T. Taniyama, T. Tsuruoka, H.Yanagimoto, H. Nawafune
Langmuir 27 11761 - 11766 2011.9
Joint Work
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Measurements of the binding of a large protein using a substrate density-controlled DNA chip Reviewed
S. Nakano, T. Kanzaki, M. Nakano, D. Miyoshi, and N. Sugimoto
Anal. Chem. 83 ( 16 ) 6768 - 6372 2011.8
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Effect of locked nucleic acid modifications on the thermal stability of noncanonical DNA structure Reviewed
J. Bhattacharyya, S. Maiti, S. Muhuri, S. Nakano, D. Miyoshi, and N. Sugimoto
Biochemistry 50 ( 34 ) 7414 - 7425 2011.8
Joint Work
DOI： 10.1021/bi200477g
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Label-free colorimetric and quantitative detection of cancer marker protein using noncrosslinking aggregation of Au/Ag nanoparticles induced by target-specific peptide probe Reviewed
Xiaohui Wang, Li Wu, Jinsong Ren, Daisuke Miyoshi, Naoki Sugimoto, and Xiaogang Qu
Biosensors and Bioelectronics 26 4804 - 4809 2011.8
Joint Work
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In situ generation of silver nanoparticles in ion-exchangeable polymer photonic crystals
T. Tsuruoka, S. Kumazaki, H. Nawafune, K. Akamatsu
Chem. Lett. 40 1233 - 1234 2011.8
Joint Work
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In situ generation of silver nanoparticles in ion-exchangeable polymer photonic crystals Reviewed
T.Tsuruoka, S.Kumazaki, H. Nawafune, K. Akamatsu
Chem. Lett. 40 1233 - 1234 2011.8
Joint Work
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Use of nucleic acid analogs for the study of nucleic acid interactions Invited Reviewed
S. Nakano, M. Fujii, and N. Sugimoto
Journal of Nucleic Acids 2011 ( 967098 ) 967098 2011.7
Joint Work
DOI： 10.4061/2011/967098
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Monolayer-Functionalized CｄTe Nanocrystals with Controlled Fluorescent Properties Based on Chemical Surface Modification
T.Tsuruoka, M.Sugiyama, R.Takahashi, H. Nawafune, K.Akamatsu
Trans.Mater.Res.Soc.Jpn 36 183 - 186 2011.6
Joint Work
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Cellular zwitterionic metabolite analogs simultaneously enhance reaction rate, thermostability, salt tolerance, and substrate specificity of alpha-glucosidase Reviewed
Eisuke Deguchi, Kazuya Koumoto
Bioorganic and Medicinal Chemistry 19 3128 - 3134 2011.4
Joint Work
Authorship：Lead author
天然の代謝産物を模倣し、化学的に合成した代謝産物アナログがα−グルコシダーゼ、β−グルコシダーゼ、アルカリフォスファターゼといった加水分解酵素の活性（反応速度、耐熱性、耐塩性、基質選択性等）を溶液に共存させるだけで向上させることを明らかとした。