Papers -
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Unusual Colorimetric Change for Alkane Solvents with a Porous Coordination Framework
Takashima Yohei, Sato Yasushi, Tsuruoka Takaaki, Akamatsu Kensuke
INORGANIC CHEMISTRY 55 ( 22 ) 11617 - 11620 2016.11
Joint Work
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Effects of trimethylamine N-oxide and urea on DNA duplex and G-quadruplex Reviewed
Y. Ueda, Y. Zouzumi, A. Maruyama, S. Nakano, N. Sugimoto, and D. Miyoshi
Sci. Tech. Adv. Mat. 17 753 - 759 2016.11
Joint Work
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細胞核DDSのためのナノトランスポーターの設計 Invited Reviewed
長濱宏治
Drug Delivery System 31 482 - 483 2016.11
Single Work
Authorship：Lead author
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Lipid-membrane-incorporated arylboronate esters as agents for boron neutron capture therapy. Reviewed International journal
Masafumi Ueda, Kengo Ashizawa, Kouta Sugikawa, Kazuya Koumoto, Takeshi Nagasaki, Atsushi Ikeda
Organic & biomolecular chemistry 15 ( 7 ) 1565 - 1569 2016.10
Joint Work
Publisher：ROYAL SOC CHEMISTRY
Arylboronate esters bearing methyl groups in both of their ortho positions were stably incorporated into lipid membranes at high concentrations without undergoing hydrolysis to the corresponding boronic acids. This method could be used in combination with previous methods to increase the maximum ratio of boron atoms in liposomal boron carriers.
DOI： 10.1039/C6OB02142E
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Thermal stability of RNA structures with bulky cations in mixed aqueous solutions Reviewed
S. Nakano, Y. Tanino, H. Hirayama, and N. Sugimoto
Biophys. J. 111 1350 - 1360 2016.10
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MEKK1-dependent phosphorylation of calponin-3 tunes cell contractility. Reviewed
Hirata H, Ku WC, Yip AK, Ursekar CP, Kawauchi K, Roy A, Guo AK, Vedula SR, Harada I, Chiam KH, Ishihama Y, Lim CT, Sawada Y, Sokabe M
Journal of Cell Science 129 ( 19 ) 3574 - 3582 2016.10
Joint Work
DOI： 10.1242/jcs.189415
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A Systematic Study on Molecular Mechanism of Pore-Forming Peptides for Discovering Antimicrobial Medicine
Y. Sekiya, H. Watanabe, K. Usui, R. Kawano
Proceedings of MicroTAS 2016 595 - 596 2016.10
Joint Work
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Increased yield of beta-glucosidase-catalyzed hydrolysis reactions in the presence of betaine-type metabolite analog Reviewed International journal
Shiro Sehata, Ryojun Suzuki, Kazuya Koumoto
BIOPROCESS AND BIOSYSTEMS ENGINEERING 40 ( 1 ) 153 - 159 2016.9
Joint Work
Publisher：SPRINGER
beta-Glucosidases (EC 3.2.1.21), abundant enzymes distributed in animals, plants and microorganism, has been generating lots of attentions for bioethanol production from cellulosic biomass. In this study, using three different origins of beta-glucosidases, glucose productivity of beta-glucosidase-catalyzed hydrolysis reactions in the presence of synthetic betaine-type metabolite analog (2-N,N,N-tri-n-butylammonium) acetate, was investigated. By the addition of the analog, the hydrolysis yields for all beta-glucosidases was highly improved from 4-13 to 64-100 %. To understand the factors affecting on the yield enhancements, the kinetic parameters, inhibition constants of end-product and temporal stability of beta-glucosidases were compared. As a result, enhancement of the yields is mainly related to the increase in the temporal stability of beta-glucosidases in the presence of the analog. The present findings lead to not only improve the glucose productivity of beta-glucosidase-catalyzed hydrolysis reaction toward bioethanol production but also apply to a new stabilization method for various unstable enzymes.
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Local thermodynamics of the water molecules around single- and double-stranded DNA studied by grid inhomogeneous solvation theory Reviewed
M. Nakano, H. Tateishi-Karimata, S. Tanaka, F. Tamab, O. Miyashita, S. Nakano, and N. Sugimoto
Chem. Phys. Lett. 660 ( 1 ) 250 - 255 2016.9
Joint Work
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Characterization of functional RNA to perform self-cleavage reaction under low pH condition
N. Sakimoto, M. Kameno, N. Sasaki, J. Kawakami
Proc. 43rd Intl. Symp. Nucleic Acid Chemistry 284 - 285 2016.9
Joint Work
Authorship：Lead author
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Discovery of a new function of curcumin which enhances its anticancer therapeutic potency Reviewed
Koji Nagahama, Tomoya Utsumi, Takayuki Kumano, Saeko Maekawa, Naho Oyama, Junji Kawakami
Scientific Reports 6 30962 2016.8
Joint Work
DOI： 10.1038/srep30962
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Curcumisome nanovesicles generated by self-assembly of curcumin amphiphiles toward cancer theranostics Reviewed
K. Nagahama, T. Utsumi, T. Kumano, S. Maekawa, N. Oyama, J. Kawakami
Scientific Reports 6 30962 2016.8
Joint Work
Authorship：Lead author
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Macrophages Exhibit a Large Repertoire of Activation States via Multiple Mechanisms of Macrophage-activating Factors. Reviewed
Sumiya Y.U., Inoue T., Ishikawa M., Inui T., Kuchiike D., Kubo K., Uto Y., Nishikata T.
Anticancer Res. 36 ( 7 ) 3619 - 3623 2016.7
Joint Work
Authorship：Lead author
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Case Report: GcMAF Treatment in a Patient with Multiple Sclerosis. Reviewed
Inui T., Katsuura G., Kubo K., Kuchiike D., Chenery L., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3771 - 3774 2016.7
Joint Work
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Case Report: A Non-small Cell Lung Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Tumor Treating Fields. Reviewed
Inui T., Amitani H., Kubo K., Kuchiike D., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3767 - 6770 2016.7
Joint Work
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Use of a ureido-substituted deoxycytidine module for DNA assemblies Invited Reviewed
S. Nakano, H. Oka, M. Fujii, and N. Sugimoto
Nucleosides, Nucleotides and Nucleic Acids 35 ( 7 ) 370 - 378 2016.5
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A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers Invited Reviewed
M. Yamaguchi, Y. Zouzumi, N. Shimada, S. Nakano, N. Sugimoto, A. Maruyama, and D. Miyoshi
Chem. Commun. 52 7446 - 7449 2016.4
Joint Work
DOI： 10.1039/C6CC02237E
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Site-Specific Control of Silica Mineralization on DNA Using a Designed Peptide Reviewed
M. Ozaki, K. Nagai, H. Nishiyama, T. Tsuruoka, S. Fujii, T. Endoh, T. Imai, K.-y. Tomizaki, K. Usui
Chem. Commun. 52 4010 - 4013 2016.3
Joint Work
Authorship：Lead author
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Site-specific control of silica mineralization on DNA using a designed peptide Reviewed
Makoto Ozaki, Kazuma Nagai, Hiroto Nishiyama, Takaaki Tsuruoka, Satoshi Fujii, Tamaki Endoh, Takahito Imai, Kin-ya Tomizaki, Kenji Usui
Chemical Communications 52 ( 21 ) 4010 - 4013 2016.3
Joint Work
DOI： 10.1039/C5CC07870A
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Development of Designed Peptides with Secondary Structure for Use in Nanobiotechnology Invited Reviewed
K.Usui
Peptide Science 2015 5 - 8 2016.3
Single Work
Authorship：Lead author