論文
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Screening of alpha-helical peptide ligands controlling a calcineurin-phosphatase activity 査読あり
Kenji Usui, Kin-ya Tomizaki, Hisakazu Mihara
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 17 ( 1 ) 167 - 171 2007年1月
出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD
In this paper, we describe an application of 202-membered fluorescently labeled peptide library designed to take an alpha-helix secondary structure. As a proof-of-concept experiment, a calmodulin (CaM)/calcineurin (Cn) pair was chosen to screen alpha-helical peptide ligands that tightly bind to CaM and also control enzymatic functions of Cn. Three peptides were successfully selected from the library by assaying Cn-phosphatase activities and peptide-CaM interactions (dual check process). The strategy using a designed peptide. library shows real promise as a peptide-based high-throughput screening system. (c) 2006 Elsevier Ltd. All rights reserved.
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Molecular Imprinting Under Molecular Crowding Conditions: an Aid to the synthesis of a High-capacity Polymeric Sorbent for Triazine Herbicides
J. Matsui, S. Goji, T. Murashima, D. Miyoshi, S. Komai, A. Shigeyasu, T. Kushida, T. Miyazawa, T. Yamada, K. Tamaki, N. Sugimoto
Anal. Chem. 2007年
共著
担当区分:筆頭著者
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Synthesis, structure and thermal stability of fully hydrophobic porphyrin-DNA conjugates 査読あり
T. Murashima, K. Hayata, Y. Saiki, J. Matsui, D. Miyoshi, T., Yamada, T. Miyazawa, and N. Sugimoto
Tetrahedron Letters 2007年
共著
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Neural-tube specific paralogous genes and their upstream regulatory sequences
西方敬人
Mem. Konan Univ., Sci. Eng. Ser ( 54 ) 75 - 88 2007年
単著
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Controlled magnetic properties of Ni nanoparticles embedded in polyimide films
S. Tomita, P. E. Jonsson, K. Akamatsu, H. Nawafune, H. Takayama
Phys. Rev. B ( 174432 ) 1 - 6 2007年
共著
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ポリエチレングリコール誘導体の予備吸着を利用する銅電析プロセスによるULSI微細配線の形成
尾山祐斗、有村英俊、赤松謙祐、縄舟秀美
表面技術 58 425 - 429 2007年
共著
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Copper/polyimide heterojunction: controlling interfacial structures through an additive-based, all-wet chemical process using ion-doped precursors
S. Ikeda, H. Yanagimoto, K. Akamatsu, H. Nawafune
Adv. Funct. Mater. 17 889 - 897 2007年
共著
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One-step synthesis of polypyrrole-coated silver nanocomposite particles and their application as a coloured particulate emulsifier
S. Fujii, A. Aichi, K. Akamatsu, H. Nawafune and Y. Nakamura
J. Mater. Chem. 17 3777 - 3779 2007年
共著
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Atomic Beam-Induced Fluorination of Polyimide and Its Application to Site-Selective Cu Metallization
M. Tagawa, K. Maeda, T. Kajita, K. Yokota, K. Akamatsu, H. Nawafune
Langmuir 23 11351 - 11354 2007年
共著
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Photosensitization of oxygen molecules by surface-modified hydrophilic porus Si
M. Fujii, N. Nishimura, H. Fumon, S. Hayashi, K. Akamatsu, T. Tsuruoka, M. Shimada, H. Katayama, D. Kovalev, B. Goller
Euro. Phys. J. D 43 193 - 196 2007年
共著
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Interactions between Peptides Containing Nucleobase Amino Acids and T7 Phages Displaying S. Cerevisiae Proteins 査読あり
S. Watanabe, K.-Y. Tomizaki, T. Takahashi, K. Usui, K. Kajikawa and H. Mihara
Biopolymers 88 ( 2 ) 131 - 140 2007年
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Photosensitization of Oxygen Molecules by Surface-Modified Hydrophilic Porus Si 査読あり
M. Fujii, N. Nishimura, H. Fumon, S. Hayashi, K. Akamatsu, T. Tsuruoka, M. Shimada, H. Katayama, D. Kovalev, B. Goller
Euro. Phys. J. D 43 193 - 196 2007年
共著
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Functional role of the cofactor on activation process of L-histidine dependent ribozyme(共著)
J. Kawakami, C. Maiya, and N. Sugimoto
Nucleic Acids Symp. Ser. 50 241 - 242 2006年11月
共著
担当区分:筆頭著者
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Galactose-PEG Dual Conjugation of b-(1→3)-D-glucan schizophyllan for antisense oligonucleotide delivery to enhance cellular uptake
甲元一也
Biomaterials, ( 27 ) 1626 - 1635 2006年11月
単著
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CpG DNA/zymosan complex to enhance cytokine secretion owing to the cocktail effect
甲元一也
Bioorg. Med. Chem. Lett ( 16 ) 1301 - 1304 2006年11月
単著
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A DNA duplex with Extremely Enhanced Thermal Stability Based on Controlled Immobilization on Gold Nanoparticles.
三好大輔
Nano Lett., ( 6 ) 491 - 495 2006年11月
単著
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Development of molecular logic gates using the structural switch of telomere DNAs
三好大輔
Nucleic Acids Symp. Ser. ( 50 ) 315 - 316 2006年11月
単著
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Molecularly Imprinting within a Single Peptide Molecule for Synthesizing a Water-soluble ATP Receptor
三好大輔
Proceedings of the International Conference of 43rd Japanese Peptide Symposium and 4th Peptide Engineering Meeting 396 - 397 2006年11月
単著
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Properties of long telomeric DNAs under cell-mimicking conditions
三好大輔
Nucleic Acids Symp. Ser. ( 50 ) 207 - 208 2006年11月
単著
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Factors regulating thermodynamic stability of DNA structures under molecular crowding conditions
三好大輔
Nucleic Acids Symp. Ser ( 50 ) 203 - 204 2006年11月
単著