論文
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Fluorescence Enhancement of Immobilized CdTe Nanocrystals on Metal Nanocrystals-Modified Substrate by Dipole Coupling 査読あり
T. Tsuruoka, M. Yamashita, M. Kumano, K. Uwajima, H. Nawafune, K. Akamatsu
Trans. Mater. Res. Soc.Jpn 39 481 - 484 2014年
共著
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Gold nanoparticle satellite nanostructures on glass substrate for dual-responsive optical sensing of organic liquids 査読あり
Y. Tanaka, A. Matsumoto, T. Tsuruoka, H. Nawafune, K. Akamatsu
Chem. Lett 43 1084 - 1085 2014年
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Controlled Synthesis of Metal-Organic Framework Films on Metal Nanoparticles by the Versatile Layer-by-Layer Assembly Approach 査読あり
T.Ohhashi, T. Tsuruoka, H. Nawafune, K. Akamatsu
Trans. Mater. Res. Soc.Jpn 39 153 - 156 2014年
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Electroless Bismuth Plating as a Peripheral Technology for SiC Power Devices 査読あり
E. Uchida, K. Tanaka, M. Okada, T. Tsuruoka, K. Akamatsu H. Nawafune
Trans. Mater. Res. Soc.Jpn 39 47 - 51 2014年
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In Situ Synthesis of Metal/Polymer Nanocomposite Thin Films on Glass Substrates by using Highly Cross-Linked Polymer Matrices with Tailorable ion exchange capabilities 査読あり
I.Toda, T.Tsuruoka, J. Matsui, T. Murashima, H. Nawafune, K. Akamatsu
RSC Adovances 4 4723 - 4726 2014年
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A Facile Template Synthesis of Asymmetric Gold Silica Heteronanoparticles 査読あり
R. Miyanohata, T. Mstsushita, T. Tsuruoka, H. Nawafune, K. Akamatsu
J. Colloid Interface Sci. 416 147 - 150 2014年
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Towards Imaging Electron Density inside Metal-Organic Framework Structures 査読あり
Yohei Takashima, De-Liang Long, Leroy Cronin
Chem. Commun 50 2271 - 2274 2014年
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Enhanced Phosphorescence Emission by Incorporating Aromatic Halides into an Entangled Coordination Framework Based on Naphthalenediimide 査読あり
Virginia Mart?nez-Mart?nez, Rebeca Sola Llano, Shuhei Furukawa, Yohei Takashima, I?igo L?pez Arbeloa, Susumu Kitagawa
ChemPhysChem 15 2517 - 2521 2014年
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In situ synthesis of metal/polymer nanocomposite thin films on glass substrates by using highly cross-linked polymer matrices with tailorable ion exchange capabilities 査読あり
I. Toda, T. Tsuruoka, J. Matsui, T. Murashima, H. Nawafune, K. Akamatsu
RSC Advances 4 4723 - 4726 2013年12月
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DOI: 10.1039/C3RA46166A
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Control of Site-Specific Silica Precipitation Using PNA Peptides and DNAs 査読あり
K. Usui, H. Nishiyama, K. Nagai, T. Tsuruoka, S. Fujii, K.-y. Tomizaki
Peptides 2013 162 - 163 2013年12月
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担当区分:筆頭著者
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Designed Peptide Libraries for Cell Analyzing Microarrays 査読あり
H. Mihara, K. Usui, H. Tsutsumi, K. Nokihara
Peptides 2013 22 - 23 2013年12月
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Peptide-DNA Hybrid G-Quadruplex Structures for Regulation of Protein Expression Depending on Protease Activity 査読あり
A. Okada, M. Taniguchi, K. Usui, N. Sugimoto
Peptides 2013 180 - 181 2013年12月
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担当区分:筆頭著者
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Cytoplasmic translocation of the retinoblastoma protein disrupts sarcomeric organization.
Araki K, Kawauchi K, Hirata H, Yamamoto M, Taya Y
eLife 2 e01228 2013年12月
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Positional Effect of 2',4'-BNA/LNA Introduction into DNA/RNA Duplexes on Thermodynamic Parameters
S. Tahara, E. Tomita, H. Nagai, S. Obika, and J. Kawakami
Proc. 40th Intl. Symp. Nucleic Acid Chemistry 190 - 191 2013年11月
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担当区分:筆頭著者
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A highly sensitive telomerase activity assay that eliminates false-negative results caused by PCR inhibitors 査読あり
H. Yaku, T. Murashima, D. Miyoshi, N. Sugimoto
Molecules 18 ( 10 ) 11751 - 11767 2013年9月
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Multiple and cooperative binding of fluorescence light-up probe thioflavin t with human telomere DNA G-quadruplex 査読あり
V. Gabelica, R. Maeda, T. Fujimoto, H. Yaku, T. Murashima, N. Sugimoto, D. Miyoshi
Biochemistry 52 ( 33 ) 5620 - 5628 2013年7月
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DOI: 10.1021/bi4006072
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Conformational changes of the phenyl and naphthyl isocyanate-DNA adducts during DNA replication and by minor groove binding molecules 査読あり
S. Nakano, Y. Uotani, Y. Sato, H. Oka, M. Fujii, and N. Sugimoto
Nucleic Acids Res. 41 8581 - 8590 2013年7月
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In situ template synthesis of one-dimensional gold nanoparticle arrays in organic nanowires 査読あり
T. Matsushita, Y. Fukumoto, T. Kawakami, T. Tsuruoka, T. Murashima, T. Yanagishita, H. Masuda, H. Nawafune, K. Akamatsu
RSC Advances 3 16243 - 16246 2013年7月
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DOI: 10.1039/C3RA42727G
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Quantitative analyses of nucleic Acid stability under the molecular crowding condition induced by cosolutes 招待あり 査読あり
Tateishi-Karimata H, Nakano S, Sugimoto N.
Curr Protoc Nucleic Acid Chem. Chapter 7 Unit7.19 2013年6月
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Systematic screening of the cellular uptake of designed alpha-helix peptides 査読あり
Kenji Usui, Takuya Kikuchi, Masayasu Mie, Eiry Kobatake, Hisakazu Mihara
BIOORGANIC & MEDICINAL CHEMISTRY 21 ( 9 ) 2560 - 2567 2013年5月
出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD
The cellular penetration (CP) activity of functional molecules has attracted significant attention as one of the most promising new approaches for drug delivery. In particular, cell-penetrating peptides (CPPs) have been studied extensively in cellular engineering. Because there have been few large-scale systematic studies to identify peptide sequences with optimal CP activity or that are suitable for further applications in cell engineering, such as cell-specific penetration and cell-selective culture, we screened and compared the cellular uptake (CU) activity of 54 systematically designed a-helical peptides in HeLa cells. Furthermore, the CU activity of 24 designed peptides was examined in four cell lines using a cell fingerprinting technique and statistical approaches. The CU activities in various cells depended on amino acid residues of peptide sequences as well as charge, a-helical content and hydrophobicity of the peptides. Notably, the mutation of a single residue significantly altered the CU ability of a peptide, highlighting the variability of cell uptake mechanisms. Moreover, these results demonstrated the feasibility of cell-selective culture by conducting cell-selective permeation and death in cultures containing two cell types. These studies may lead to further peptide library design and screening for new classes of CPPs with useful functions. (C) 2013 Elsevier Ltd. All rights reserved.