Presentations -
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Optimizing Separation and Quantification of Oligonucleotides Impurities with 2D-LC/MS
Atsuko Naito, Hiroshi Sezaki, Akio Hayashi, Hirokazu Sawada, Takao Inoue, Junji Kawakami, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Suppression of RNase H recognition by distortion of DNA/RNA structure
Tomoka Akita, Ayumu Kashiwagi, Renshin Sano, Elisa Tomita-Sudo, Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Impurity Profiling of Oligonucleotide Therapeutics using LCMS-Q-TOF
Risa Suzuki, Takashi Nishikaze, Noriko Kato, Kosuke Uchiyama, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Analysis of oligonucleotides impurities produced by light irradiation in solution
Taku Ishigaki, Elisa Tomita-Sudo, Takao Yamaguchi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Efficient Methods Development of Oligonucleotides separation by Reversed-Phase Ion-Pair Chromatography
Shinichi Fujisaki, Risa Suzuki, Keiko Matsumoto, Kyoko Watanabe, Junji Kawakami, Takao Inoue, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Method development for native analysis of siRNA using LC-MS
Sezaki Hiroshi, Akio Hayashi, Atsuko Naito, Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Sequencing and Deletion Site Confirmation of Morpholino Antisense Oligonucleotides
Kaoru Karasawa, Eva Duchoslav, Lyle Burton, Junji Kawakami, Takashi Baba
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Studies on analytical conditions for antisense phosphorothioate oligonucleotides by RPIP-LC and AEX-LC
Hong Wei, Tsuyoshi Ogihara, Yuka Otomaru, Ryuta Akamine, Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Effect of sugar-modifications and nucleobases on amidite solution stability
Kosuke Chiba, Ajaya Ram Shrestha, Taiki Fujisue, Takashi Osawa, Tsuyoshi Maekawa, Junji Kawakami, Takao Inoue, Satoshi Obika, Tadashi Umemoto
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Thermodynamic stability modulation of RNA/DNAduplex introducing ENA in DNA strand
Yoshiyuki Onishi, Tomoka Akita, Elisa Tomita-Sudo, Shizuka Közaki, Renshin Sano, Ayumu Kashiwagi, Riki Hatakenaka,Makoto Koizumi, Junji Kawakami
Gordon Research Conferences (Nucleosides, Nucleotides and Oligonucleotides) (Salve Regina University) 2023.6
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Efficient Method Development of Oligonucleotides by Reversed-Phase Ion-Pair Chromatography
Shinichi Fujisaki, Risa Suzuki, Junji Kawakami, Takao Inoue, Satoshi Obika, Kyoko Watanabe
TIDES USA 2023 2023.5
Event date： 2023.5
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In-process monitoring of oligonucleotide therapeutics purification using MALDI-MS
Takashi Nishikaze, Junji Kawakami, Takao Inoue, Satoshi Obika
TIDES USA 2023 2023.5
Event date： 2023.5
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ベンダーフリーな定量ソフトウェアを用いた核酸医薬品不純物の定量解析
髙嶺 竜太朗, 山口 卓男, 井上 貴雄, 小比賀 聡, 川上 純司
日本薬学会第143年会 (北海道大学) 2023.3
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核酸医薬品開発の現状と課題 −国産の核酸医薬品創出に向けた取り組み−
川上 純司、井上 貴雄、小比賀 聡
日本薬学会第143年会 (北海道大学) 2023.3
Event date： 2023.3
Country：Japan
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核酸医薬に含まれる不純物のCDスペクトルを用いた検出
石垣 卓, 大山 泰史, 鈴木 仁子, 神前 静香, 秋田 智香, 井上 貴雄, 小比賀 聡, 川上 純司
日本薬学会第143年会 (北海道大学) 2023.3
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修飾の違いによるアンチセンス核酸の標的配列への結合親和性と結合速度の比較
嵜本 捺愛, 藤木 秀一郎, 畠中 陸希, 小比賀 聡, 川上 純司
日本薬学会第143年会 (北海道大学) 2023.3
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核酸医薬品開発の現状と課題 －国産の核酸医薬品創出に向けた取り組み－ Invited
川上 純司, 井上 貴雄, 小比賀 聡
日本薬学会第143年会 (北海道大学) 2023.3
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ENAを導入した2’-OMe RNA鎖およびDNA鎖の相補鎖RNA認識能
冨田 恵麗沙, 秋田 智香, 柏木 歩夢, 佐野 蓮心, 大西 朗之, 小泉 誠, 川上 純司
日本薬学会第143年会 (北海道大学) 2023.3
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Effects of inner wall treatment of HPLC columns on oligonucleotide analysis
Emi Saito, Harei Sakurai, Hirokazu Nankai, Takao Inoue, Junji Kawakami, Satoshi Obika
TIDES ASIA 2023, Oligonucleotide & Peptide Therapeutics 2023.3
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Oligonucleotide Sequence Confirmation
Takahide Hiramatsu, Takashi Nishikaze, Ryo Kubota, Noriko Kato, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
TIDES ASIA 2023, Oligonucleotide & Peptide Therapeutics 2023.3