Presentations -
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Efficient Method Development and Identification of Oligonucleotides Therapeutics Impurities
Risa Suzuki, Shinichi Fujisaki, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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Effect of bridged nucleic acid introduction on the flexibility of oligonucleotides
Tomoka Akita, Elisa Tomita-Sudo, Shin Itoh, Nae Sakimoto, Takeshi Masuda, Akifumi Nakamura, Yoshiyuki Onishi, Makoto Koizumi, Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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Assessment of Subtle HOS Changes in Oligonucleotide Therapeutics Using High-Throughput Circular Dichroism Spectrometer HTCD Plus and a program qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita, Takao Inoue, Satoshi Obika, Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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核酸のFoldingと相互作用 −その検出とCMCにおける重要性− Invited
川上 純司
医薬品関連マテリアルズオープンプラットフォーム（MOP） (物質・材料研究機構 高分子・バイオ材料研究センター) 2023.10
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The Oligonucleotide CMC project supported by AMED Invited
Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Purification of oligonucleotide using continuous chromatography (MSCGP)
Mayuko Mouri, Kiyotaka Takimoto, Eigo Muto, Junji Kawakami, Takao Inoue, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Evaluation of Oligonucleotide Therapeutics Using the High Throughput Circular Dichroism Spectrometer HTCD Plus and the Special Similarity Evaluation Software qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita, Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Rapid impurity monitoring of oligonucleotide therapeutics using benchtop MALDI-TOF MS
Takashi Nishikaze, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Confirmation and quantitative evaluation of deletion/PS to PO conversion sites of oligonucleotides
Chie Inagaki, Noriyuki Iwasaki, Junji Kawakami, Takao Inoue, Obika Satoshi, Kaoru Karasawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Optimizing Separation and Quantification of Oligonucleotides Impurities with 2D-LC/MS
Atsuko Naito, Hiroshi Sezaki, Akio Hayashi, Hirokazu Sawada, Takao Inoue, Junji Kawakami, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Suppression of RNase H recognition by distortion of DNA/RNA structure
Tomoka Akita, Ayumu Kashiwagi, Renshin Sano, Elisa Tomita-Sudo, Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Impurity Profiling of Oligonucleotide Therapeutics using LCMS-Q-TOF
Risa Suzuki, Takashi Nishikaze, Noriko Kato, Kosuke Uchiyama, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Analysis of oligonucleotides impurities produced by light irradiation in solution
Taku Ishigaki, Elisa Tomita-Sudo, Takao Yamaguchi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Efficient Methods Development of Oligonucleotides separation by Reversed-Phase Ion-Pair Chromatography
Shinichi Fujisaki, Risa Suzuki, Keiko Matsumoto, Kyoko Watanabe, Junji Kawakami, Takao Inoue, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Method development for native analysis of siRNA using LC-MS
Sezaki Hiroshi, Akio Hayashi, Atsuko Naito, Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Sequencing and Deletion Site Confirmation of Morpholino Antisense Oligonucleotides
Kaoru Karasawa, Eva Duchoslav, Lyle Burton, Junji Kawakami, Takashi Baba
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Studies on analytical conditions for antisense phosphorothioate oligonucleotides by RPIP-LC and AEX-LC
Hong Wei, Tsuyoshi Ogihara, Yuka Otomaru, Ryuta Akamine, Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Effect of sugar-modifications and nucleobases on amidite solution stability
Kosuke Chiba, Ajaya Ram Shrestha, Taiki Fujisue, Takashi Osawa, Tsuyoshi Maekawa, Junji Kawakami, Takao Inoue, Satoshi Obika, Tadashi Umemoto
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7