Presentations -
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Identification of a novel guanine-derived impurity in oligonucleotides and investigation of its formation factors
Harei Sakurai, Emi Saito, Hirokazu Nankai, Takeshi Osawa, Takao Inoue, Junji Kawakami, Satoshi Obika
TIDES ASIA 2024, Oligonucleotide & Peptide Therapeutics 2024.3
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Sequence confirmation of partially deaminated oligonucleotide analogues using 2D-LC/MS
Emi Saito, Harei Sakurai, Hirokazu Nankai, Takao Inoue, Junji Kawakami, Satoshi Obika
TIDES ASIA 2024, Oligonucleotide & Peptide Therapeutics 2024.3
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核酸医薬品の評価技術（構造安定性、分離分析を中心に） Invited
川上純司
Shimadzu Biopharma Webinar 2023 Day5『核酸医薬品の開発・品質管理における分析技術の最前線』 2024.2
Event date： 2024.2
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オリゴ核酸の分析におけるHFIPの品質およびMS感度の比較
廣瀬 恒久, 尾崎 誠, 桑山 知美, 川上 純司, 下間志士
第15回JBFシンポジウム (みやこめっせ) 2024.2
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Ligation reaction on Capped RNA substrates by a Ligase Ribozyme
Nae Sakimoto, Riki Hatakenaka, Emily Matsusaka, Natsuki Doi, Akane Kiyose, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
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Sequence-dependent effects on kinetic parameters of nucleic acid duplex formation
Elisa Tomita-Sudo, Tomoka Akita, Renshin Sano, Ayumu Kashiwagi, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
Event date： 2023.11
Country：Japan
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Sequence-dependent effects on kinetic parameters of nucleic acid duplex formation
Elisa Tomita-Sudo, Tomoka Akita, Renshin Sano, Ayumu Kashiwagi, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
Event date： 2023.11
Country：Japan
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Sequences that destabilize DNA/RNA duplexes
Shizuka Közaki, Ayumu Kashiwagi, Shuichiro Fujiki, Tomoka Akita, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
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Efficient Method Development and Identification of Oligonucleotides Therapeutics Impurities
Risa Suzuki, Shinichi Fujisaki, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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Effect of bridged nucleic acid introduction on the flexibility of oligonucleotides
Tomoka Akita, Elisa Tomita-Sudo, Shin Itoh, Nae Sakimoto, Takeshi Masuda, Akifumi Nakamura, Yoshiyuki Onishi, Makoto Koizumi, Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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Assessment of Subtle HOS Changes in Oligonucleotide Therapeutics Using High-Throughput Circular Dichroism Spectrometer HTCD Plus and a program qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita, Takao Inoue, Satoshi Obika, Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
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核酸のFoldingと相互作用 −その検出とCMCにおける重要性− Invited
川上 純司
医薬品関連マテリアルズオープンプラットフォーム（MOP） (物質・材料研究機構 高分子・バイオ材料研究センター) 2023.10
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The Oligonucleotide CMC project supported by AMED Invited
Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Purification of oligonucleotide using continuous chromatography (MSCGP)
Mayuko Mouri, Kiyotaka Takimoto, Eigo Muto, Junji Kawakami, Takao Inoue, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Evaluation of Oligonucleotide Therapeutics Using the High Throughput Circular Dichroism Spectrometer HTCD Plus and the Special Similarity Evaluation Software qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita, Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Rapid impurity monitoring of oligonucleotide therapeutics using benchtop MALDI-TOF MS
Takashi Nishikaze, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
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Confirmation and quantitative evaluation of deletion/PS to PO conversion sites of oligonucleotides
Chie Inagaki, Noriyuki Iwasaki, Junji Kawakami, Takao Inoue, Obika Satoshi, Kaoru Karasawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7