Presentations -
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Sequence-dependent effects on kinetic parameters of nucleic acid duplex formation
Elisa Tomita-Sudo, Tomoka Akita, Renshin Sano, Ayumu Kashiwagi, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
Event date： 2023.11
Country：Japan
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Sequences that destabilize DNA/RNA duplexes
Shizuka Közaki, Ayumu Kashiwagi, Shuichiro Fujiki, Tomoka Akita, Junji Kawakami
The 50th International Symposium on Nucleic Acids Chemistry The 7th Annual Meeting of Japan Society of Nucleic Acids Chemistry (Miazaki Civic Plaza) 2023.11
Event date： 2023.11
Country：Japan
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Efficient Method Development and Identification of Oligonucleotides Therapeutics Impurities
Risa Suzuki, Shinichi Fujisaki, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
Event date： 2023.10
Country：Spain
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Effect of bridged nucleic acid introduction on the flexibility of oligonucleotides
Tomoka Akita, Elisa Tomita-Sudo, Shin Itoh, Nae Sakimoto, Takeshi Masuda, Akifumi Nakamura, Yoshiyuki Onishi, Makoto Koizumi and Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
Event date： 2023.10
Country：Spain
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Assessment of Subtle HOS Changes in Oligonucleotide Therapeutics Using High-Throughput Circular Dichroism Spectrometer HTCD Plus and a program qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita, Takao Inoue, Satoshi Obika, Junji Kawakami
19th Annual Meeting of the Oligonucleotide Therapeutics Society (OTS, at Barcelona) (Fira de Barcelona) 2023.10
Event date： 2023.10
Country：Spain
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核酸のFoldingと相互作用 Invited
川上 純司
医薬品関連マテリアルズオープンプラットフォーム（MOP） (物質・材料研究機構 高分子・バイオ材料研究センター) 2023.10 川上 亘作
Event date： 2023.10
Country：Japan
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架橋型核酸による標的結合親和性向上の塩基配列依存性
秋田智香、冨田恵麗沙、川上純司
超異分野学会大阪大会2023 2023.8
Event date： 2023.8
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The Oligonucleotide CMC project supported by AMED Invited
Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Purification of oligonucleotide using continuous chromatography (MSCGP)
Mayuko Mouri, Kiyotaka Takimoto, Eigo Muto, Junji Kawakami, Takao Inoue, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Evaluation of Oligonucleotide Therapeutics Using the High Throughput Circular Dichroism Spectrometer HTCD Plus and the Special Similarity Evaluation Software qHOS
Taiji Oyama, Satoko Suzuki, Taku Ishigaki, Shizuka Közaki, Tomoka Akita,Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Rapid impurity monitoring of oligonucleotide therapeutics using benchtop MALDI-TOF MS
Takashi Nishikaze, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Confirmation and quantitative evaluation of deletion/PS to PO conversion sites of oligonucleotides
Chie Inagaki, Noriyuki Iwasaki, Junji Kawakami, Takao Inoue, Obika Satoshi, Kaoru Karasawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Optimizing Separation and Quantification of Oligonucleotides Impurities with 2D-LC/MS
Atsuko Naito, Hiroshi Sezaki, Akio Hayashi, Hirokazu Sawada,Takao Inoue, Junji Kawakami, Obika Satoshi
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Suppression of RNase H recognition by distortion of DNA/RNA structure
Tomoka Akita, Ayumu Kashiwagi, Renshin Sano, Elisa Tomita-Sudo, Takao Inoue, Obika Satoshi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Impurity Profiling of Oligonucleotide Therapeutics using LCMS-Q-TOF
Risa Suzuki, Takashi Nishikaze, Noriko Kato, Kosuke Uchiyama, Junji Kawakami, Takao Inoue, Satoshi Obika, Yoshihiro Hayakawa
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Analysis of oligonucleotides impurities produced by light irradiation in solution
Taku Ishigaki, Elisa Tomita-Sudo, Takao Yamaguchi, Junji Kawakami
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Efficient Methods Development of Oligonucleotides separation by Reversed-Phase Ion-Pair Chromatography
Shinichi Fujisaki, Risa Suzuki, Keiko Matsumoto, Kyoko Watanabe, Junji Kawakami, Takao Inoue, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Method development for native analysis of siRNA using LC-MS
Sezaki Hiroshi, Akio Hayashi, Atsuko Naito , Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Sequencing and Deletion Site Confirmation of Morpholino Antisense Oligonucleotides
Kaoru Karasawa, Eva Duchoslav, Lyle Burton, Junji Kawakami, Takashi Baba
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan
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Studies on analytical conditions for antisense phosphorothioate oligonucleotides by RPIP-LC and AEX-LC
Hong Wei, Tsuyoshi Ogihara, Yuka Otomaru, Ryuta Akamine, Takao Inoue, Junji Kawakami, Satoshi Obika
The 8th Annual Meeting of the Nucleic Acids Therapeutics Society of Japan 2023.7
Event date： 2023.7
Country：Japan