写真a

WATANABE Junji

Position

Professor

Research Field

Life Science / Biomaterials, Nanotechnology/Materials / Polymer chemistry, Nanotechnology/Materials / Composite materials and interfaces, Nanotechnology/Materials / Polymer materials

Homepage URL

http://www.chem.konan-u.ac.jp/DBM/

Mail Address

E-mail address

External Link

Graduating School 【 display / non-display

  • Osaka Prefecture University   Faculty of Engineering   Department of Applied Chemistry   Graduated

    1989.4 - 1993.3

Graduate School 【 display / non-display

  • Japan Advanced Institute of Science and Technology   Graduate School, Division of Materials Science   Doctor's Course   Completed

    1997.10 - 2000.6

  • Osaka Prefecture University   Graduate School, Division of Engineering   Master's Course   Completed

    1993.4 - 1995.3

Studying abroad experiences 【 display / non-display

  • 2004.9
    -
    2004.10

    Angstrom Laboratory, Uppsala University   International Exchange Programs on Nanotechnology Signed by Sweden and Japan

  • 1999.11
    -
    2000.1

    Korea Institute of Science and Technology (KIST)   Visiting Scientist

Campus Career 【 display / non-display

  • KONAN UNIVERSITY   Faculty of Science and Engineering   Faculty of Science and Engineering Department of Chemistry of Functional Molecules   Professor

    2012.4

  • KONAN UNIVERSITY   Faculty of Science and Engineering   Faculty of Science and Engineering Department of Chemistry of Functional Molecules   Associate Professor

    2009.4 - 2012.3

External Career 【 display / non-display

  • 大阪大学大学院工学研究科応用化学専攻

    2007.4 - 2009.3

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    Country:Japan

  • 大阪大学大学院工学研究科応用化学専攻

    2005.5 - 2007.3

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    Country:Japan

  • 東京大学大学院工学系研究科マテリアル工学専攻

    2001.4 - 2005.5

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    Country:Japan

  • 東京大学大学院工学系研究科金属工学専攻

    2000.7 - 2001.3

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    Country:Japan

  • 北陸先端科学技術大学院大学

    1997.4 - 1997.9

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    Country:Japan

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Papers 【 display / non-display

  • Development of a Powder with Water-Resistance and Easy-Wash-Off Properties Using Poly (Trimethylene Carbonate) Derivatives and Its Application to Cosmetics Reviewed

    Chihiro Iwamoto, Ai Oyama, Takayuki Kumei, Junji Watanabe

    Journal of Society of Cosmetic Chemists of Japan   52 ( 3 )   197 - 204   2018.9

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    Joint Work

    Functional properties of the foundation and sunscreen products need to be long lasting because they are applied to the skin during long time in a day. Thus, the surface of the powder in cosmetics is coated with hydrophobic agents to make it water resistant. However, the water-resistant property of the powder makes it difficult to wash-off with water easily. To solve this problem, we focused on two types of poly(trimethylene carbonate) (PTMC) derivatives which show spontaneous surface rearrangements depending on wet or dry conditions. We found out that PTMC with poly(dimethylsiloxane) (PDMS-PTMC) and poly(ethylene glycol) monomethyl ether (mPEG-PTMC) showed change in contact angle because of the surface rearrangement of polymers under the wet condition. The response time under wet condition and change in contact angle were able to be controlled by the polymer chain length and blend ratio of PDMS-PTMC and mPEG-PTMC. PDMS-PTMC and mPEG-PTMC polymer-coated powder showed hydrophobic for a certain period, and then became hydrophilic after a certain period in water. Furthermore, by using a powder coated with PDMS-PTMC and mPEG-PTMC with the optimal polymer chain length and blend ratio for the powdery foundation, it is possible to develop a product that is both long lasting and easily wash-off.

    DOI: 10.5107/sccj.52.197

    Other Link: http://orcid.org/0000-0002-6795-2554

  • A Rapid and Specific C-Reactive Protein Immunoassay Driven by an Electrophoresis System Based on Protein Enrichment in a 3D Filter Reviewed International coauthorship

    Nanoscience and Nanotechnology Letters   9 ( 4 )   425 - 432   2017.4

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    Joint Work

    A rapid, sensitive and simple electrophoresis immunoassay was developed using a positive polyelectrolyte multilayer (PEM)-modified cellulose acetate (CA) membrane filter (PEM-CA). C-reactive protein (CRP), a cardiac and inflammation marker, was used as a measurement model. This rapid immunoassay was carried out using electrophoresis to drive the antigen movement, thus allowing local condensation of CRP in the proximity of an antibody-enriched PEM-CA filter. This overcame the diffusion resistance that normally dictates the time required for conventional ELISA. Moreover, electrophoresis could enhance the CRP specificity in a mixed solution of serum proteins because each protein has a unique electrophoretic velocity. The calibration curve for electrophoresis detection had a wide linear range of concentration from 0.013 to 50 nM, with a limit of detection of 33 pM, regardless of the presence of other proteins. The incubation time for antigen-antibody reaction was only 2 min, or about 1/30th of the time required for a conventional ELISA system. We conclude that this electrophoresis detection system should be developed further as a rapid, precise, and simple system for various immunosensors, using PEM-modified membrane filters.

    DOI: 10.1166/nnl.2017.2328

    Other Link: http://orcid.org/0000-0002-6795-2554

  • Dual Electrophoresis Detection System for Rapid and Sensitive Immunoassays with Nanoparticle Signal Amplification Reviewed International coauthorship

    Scientific Reports   7   42562   2017.2

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    Joint Work

    An electrophoretic technique was combined with an enzyme-linked immunosorbent assay (ELISA) system to achieve a rapid and sensitive immunoassay. A cellulose acetate filter modified with polyelectrolyte multilayer (PEM) was used as a solid substrate for three-dimensional antigen-antibody reactions. A dual electrophoresis process was used to induce directional migration and local condensation of antigens and antibodies at the solid substrate, avoiding the long diffusion times associated with antigen-antibody reactions in conventional ELISAs. The electrophoretic forces drove two steps in the ELISA process, namely the adsorption of antigen, and secondary antibody-labelled polystyrene nanoparticles (NP-Ab). The total time needed for dual electrophoresis-driven detection was just 4 min, nearly 2 h faster than a conventional ELISA system. Moreover, the rapid NP-Ab electrophoresis system simultaneously achieved amplification of the specific signal and a reduction in noise, leading to a more sensitive NP-Ab immunoassay with a limit of detection (LOD) of 130 fM, and wide range of detectable concentrations from 0.13 to 130 pM. These results suggest that the combination of dual electrophoresis detection and NP-Ab signal amplification has great potential for future immunoassay systems.

    DOI: 10.1038/srep42562

    Other Link: http://orcid.org/0000-0002-6795-2554

  • Hydrophilic Polyelectrolyte Multilayers Improve the ELISA System: Antibody Enrichment and Blocking Free Reviewed International coauthorship

    Polymers   9 ( 2 )   51 - 64   2017.2

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    Joint Work

    In this study, polyelectrolyte multilayers were fabricated on a polystyrene (PS) plate using a Layer-by-Layer (LbL) self-assembly technique. The resulting functional platform showed improved performance compared with conventional enzyme-linked immunosorbent assay (ELISA) systems. Poly(diallyldimethylammonium chloride) (PDDA) and poly(acrylic acid) (PAA) were used as cationic and anionic polyelectrolytes. On the negatively-charged (PDDA/PAA)3 polyelectrolyte multilayers the hydrophilic PAA surface could efficiently decrease the magnitude of the noise signal, by inhibiting nonspecific adsorption even without blocking reagent adsorption. Moreover, the (PDDA/PAA)3 substrate covalently immobilized the primary antibody, greatly increasing the amount of primary antibody adsorption and enhancing the specific detection signal compared with a conventional PS plate. The calibration curve of the (PDDA/PAA)3 substrate showed a wide linear range, for concentrations from 0.033 to 33 nM, a large specific signal change, and a detection limit of 33 pM, even though the conventional blocking reagent adsorption step was omitted. The (PDDA/PAA)3 substrate provided a high-performance ELISA system with a simple fabrication process and high sensitivity; the system presented here shows potential for a variety of immunosensor applications.

    DOI: 10.3390/polym9020051

    Other Link: http://orcid.org/0000-0002-6795-2554

  • Design and synthesis of an amphiphilic graft hydrogel having a hydrophobic domain formed by multiple interactions Reviewed

    Materials Science and Engineering: C   68   65 - 69   2016.11

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Books and Other Publications 【 display / non-display

  • アモルファスポリマーが創り出す組織再生用マテリアル,先端バイオマテリアルハンドブック

    渡邉順司( Role: Sole author)

    エヌ・ティー・エス  2012.6 

  • 交互浸漬法による高分子ゲル/アパタイト,バイオミネラリゼーションとそれに倣う新機能材料の創製,加藤隆史監修

    渡邉順司,明石 満( Role: Joint author ,  213–224)

    シーエムシー出版  2007.1 

  • Biomineralization of Hydrogels Based on Bioinspired Assemblies for Injectable Biomaterials, In Bio-Inorganic Hybrid Nanomaterials, Ed. by Eduardo Ruiz-Hitzky, Katsuhiko Ariga, and Yuri Lvov

    Junji Watanabe and Mitsuru Akashi( Role: Joint author ,  193–208)

    Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany  2007.1 

  • 骨修復機能性ファイバーの設計,“ファイバー”スーパーバイオミメティックス〜近未来の新技術創成〜

    渡邉順司,明石 満( Role: Joint author ,  910–915)

    エヌ・ティー・エス  2006.10 

  • 高度なバイオ工学を実現するリン脂質サーフェイステクノロジー,界面活性剤・両親媒性高分子の最新機能

    石原一彦,渡邉順司,高井まどか( Role: Joint author ,  223–232)

    シーエムシー出版  2005.6 

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Review Papers (Misc) 【 display / non-display

  • 両親媒性高分子の添加による多孔性シリコーンゴムの創製と油水分離特性 Invited

    渡邉順司,鈴木はる菜

    ポリマーTECH   16   8 - 15   2023.2

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    Authorship:Lead author   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:化学工業社  

  • 結晶−非晶ブロックポリマーによる界面特性の変換

    渡邉順司,松田侑子,池田能幸

    化学工業   63 ( 5 )   342 - 347   2012.5

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    Authorship:Lead author   Publishing type:Article, review, commentary, editorial, etc. (trade magazine, newspaper, online media)   Publisher:化学工業社  

  • 創傷被覆材への応用にむけたポリ(トリメチレンカーボネート)を基盤とした環境応答型ポリマー

    渡邉順司

    高分子論文集   69 ( 3 )   89 - 101   2012.3

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    Authorship:Lead author   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:高分子学会  

  • 電気化学的アプローチによる有機—無機ハイブリッドの創製と硬組織適合材料への応用

    渡邉順司

    バイオマテリアル   27 ( 1 )   38 - 48   2009.1

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    Authorship:Lead author   Publishing type:Article, review, commentary, editorial, etc. (international conference proceedings)   Publisher:日本医学館  

  • 電気化学的手法による有機—無機複合化プロセスの開発

    渡邉順司,明石 満

    化学工業   59 ( 11 )   852 - 858   2008.11

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    Authorship:Lead author   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Publisher:化学工業社  

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Presentations 【 display / non-display

  • 高分子鎖の特徴を生かした材料表面およびバルクの機能化 Invited

    渡邉順司

    日本接着学会 粘着研究会 第186回例会  (東京都文京区)  2023.1 

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    Event date: 2023.1

  • Environmentally Responsive Biointerface by Dynamic Molecular Motion of Amorphous Polymer Invited

    Junji Watanabe

    IUPAC MACRO 2014  (Chiang Mai, Thailand) 

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    Event date: 2014.7

  • 電気化学的アプローチによる有機—無機ハイブリッドの創製と硬組織適合材料への応用 Invited

    渡邉順司

    日本バイオマテリアル学会シンポジウム2008  (東京都文京区) 

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    Event date: 2008.11

  • 硬組織適合型材料の設計と新展開 Invited

    渡邉順司,明石満

    第58回医用高分子研究会  (大阪府吹田市) 

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    Event date: 2008.3

  • バイオマテリアルを指向した高分子材料のミネラリゼーション Invited

    渡邉順司,明石満

    九州地区高分子若手研究会  (長崎市) 

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    Event date: 2007.11

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Industrial property rights 【 display / non-display

  • 着氷雪防止剤およびそれを被覆した構造物

    須田修平,渡邉順司,森山昇斗

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    Application no:2019-233908

    Announcement no:2021-102682

    Patent/Registration no:特許第7337686号

  • 表面処理粉体

    岩本千紘,粂井貴行,渡邉順司

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    Application no:2014-174248

    Announcement no:2016-050212

    Patent/Registration no:特許第5795110号

  • 表面処理剤

    岩本千紘,粂井貴行,渡邉順司

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    Application no:2014-117315

    Announcement no:2015-229740

    Patent/Registration no:特許第6376850号

  • ポリマー被覆粒子

    石原一彦,高井まどか,渡邉順司,松井謙次

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    Application no:2005–210656

    Announcement no:2007–022886

    Patent/Registration no:特許第5150890号

  • 免疫学的活性物質の測定方法

    石原一彦,渡邉順司,黒澤 茂

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    Application no:2003–326829

    Announcement no:2005–091236

    Patent/Registration no:特許第4278469号

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Academic Awards Received 【 display / non-display

  • 第12回日本ゴム協会科学技術奨励賞

    2020.5   日本ゴム協会  

    渡邉順司

  • 平成20年度日本バイオマテリアル学会科学奨励賞

    2008.11   日本バイオマテリアル学会  

    渡邉順司

  • 日本化学会第86春季年会 第20回若い世代の特別講演会特別講演証

    2006.3   日本化学会  

    渡邉順司

Grant-in-Aid for Scientific Research 【 display / non-display

  • イオン性高分子鎖をもつエラストマーによる高速親水化フィルターの創製と溶質透過制御

    2011.4 - 2014.3

    JSPS Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research(C)

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    非晶性高分子の代表である高分子エラストマーとイオン性の親水性高分子鎖をつなげたブロック共重合体を設計し、溶質透過膜を創製する。

  • 電気化学的手法により創製された有機—無機複合材料の特性解析とバイオ機能解析

    2007.4 - 2010.3

    JSPS Grants-in-Aid for Scientific Research Grant-in-Aid for Exploratory Research

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    ハイドロゲルや多孔質膜のような有機材料の微細空孔内部を活用し、無機化合物を析出・生成させる有機—無機ハイブリッド材料を創製する。

Other External funds procured 【 display / non-display

  • 単分散で長期安定性を有するサンスクリーン用ポリマーコロイドの開発

    2011.12 - 2012.7

    科学技術振興機構  科学技術振興機構 研究成果最適展開支援事業(A-STEP)探索タイプ

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    生体適合性の高いポリマーから作り出されたコロイドに配合薬剤を閉じ込め、発汗による湿った環境下で充分に機能するサンスクリーン用基剤を開発する。

  • 高速親水化ポリマーの塗布による創傷被覆ガーゼのイノベーション

    2011.10 - 2012.9

    科学技術振興機構  科学技術振興機構 研究成果最適展開支援事業(A-STEP)シーズ顕在化タイプ

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    創傷部の治癒過程で発生するガーゼの癒着が回避できる創傷被覆ガーゼの開発を行う。

  • 創傷部での癒着を回避できるガーゼ開発のための高速親水化ポリマー

    2010.10 - 2011.3

    科学技術振興機構  科学技術振興機構 研究成果最適展開支援事業(A-STEP)探索タイプ

Preferred joint research theme 【 display / non-display

  • ポリマーアロイの創製

  • コロイドマテリアルの創製

  • 医療診断デバイスの創製

  • 有機ー無機複合材料の創製

  • 高分子材料による界面創製

 

Committee Memberships 【 display / non-display

  • 2024.6 - 2025.3   日本MRS  日本MRS第34回年次大会 代表および連絡オーガナイザー

  • 2024.4 - 2025.3   日本MRS  日本MRS第34回年次大会 組織委員会委員

  • 2023.6 - 2024.3   日本MRS  日本MRS第33回年次大会 代表および連絡オーガナイザー

  • 2023.5   日本ゴム協会  編集委員会 編集委員長

  • 2023.4 - 2024.3   日本MRS  日本MRS第33回年次大会 組織委員会委員

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Social Activities 【 display / non-display

  • 関西ゴム技術研修所 副所長

    Role(s): Planner

    2019.8 - 2023.6

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    Audience: General

  • 関西ゴム技術研修所 講師 「材料課目 熱可塑性エラストマー」

    Role(s): Lecturer

    2015.9

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    Audience: General

  • 神戸ゴム科学研究会 委員

    Role(s): Organizing member

    2015.4

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    Audience: Company

  • Editorial Board of Biomaterials and Biomechanics in Bioengineering

    2015.1 - 2019.12

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    Audience: Researchesrs

  • 北陸先端科学技術大学院大学 教育連携客員教授

    Role(s): Advisor

    2014.12 - 2018.3

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    Audience: Teachers

    教育連携アドバイザー

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Qualification acquired 【 display / non-display

  • Hazardous Material Handler (first kind)

  • Usual Car License (first kind)