Papers - MIYOSHI Daisuke
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Shikhar Tyagi, Sarika Saxena, Nikita Kundu, Taniya Sharma, Amlan Chakraborty, Sarvpreet Kaur, Daisuke Miyoshi, Jadala Shankaraswamy
RSC Advances 9 40255 - 40262 2019.12
Joint Work
We described a novel synthetic peptide in which a glutamine residue binds through hydrogen bonding to a guanine-base and a trytophan residue intercalates with K+ resulting in stabilization of a human telomeric G-quadruplex with high selectivity over its complementary c-rich strand and a double-stranded DNA and its complementary C-rich strand. This peptide offers great potential for cancer treatment by inhibiting the telomere extension by telomerase.
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The RAS mRNA G-quadruplex: making undruggable cancer targets druggable
Keiko Kawauchi, Wataru Sugimoto, Daisuke Miyoshi
The Atlas of Science 2019.10
Joint Work
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細胞の分子夾雑環境における核酸構造と核酸構造リガンドの挙動 ~細胞内でも望みの機能を発現する分子の合理設計に向けて~
三好大輔
生命化学研究レター 58 ( 1 ) 17 - 21 2019.4
Single Work
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Osmolyte-Enhanced Protein Synthesis Activity of a Reconstituted Translation System Reviewed
Yoshiki Moriizumi, Kazuhito V. Tabata, Daisuke Miyoshi, Hiroyuki Noji
ACS Synth Biol. 8 ( 3 ) 557 - 567 2019.2
Joint Work
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Metal sensitive and DNA concentration dependent structural rearrangement of short oligonucleotide into large suprastructures Reviewed
J. Shankaraswamy, Shikhar Tyagi, Anju Singh, Daisuke Miyoshi, Sarika Saxena
Journal of Biomolecular Structure and Dynamics 37 ( 9 ) 2211 - 2218 2018.12
Joint Work
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An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex Reviewed
Keiko Kawauchi, Wataru Sugimoto, Takatoshi Yasui, Kohei Murata, Katsuhiko Itoh, Kazuki Takagi, Takaaki Tsuruoka, Kensuke Akamatsu, Hisae Tateishi-Karimata, Naoki Sugimoto, and Daisuke Miyoshi
Nature Communicationsvolume 9 2271 2018.6
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DNA G-Wire Formation Using an Artificial Peptide is Controlled by Protease Activity Reviewed
Kenji Usu, Arisa Okada, Shungo Sakashita, Masayuki Shimooka, Takaaki Tsuruoka, Shu-ichi Nakano, Daisuke Miyoshi, Tsukasa Mashima, Masato Katahira and Yoshio Hamada
Molecules 22 1991 2017.11
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Highly Sensitive Telomerase Assay Insusceptible to Telomerase and Polymerase Chain Reaction Inhibitors for Cervical Cancer Screening Using Scraped Cells. Reviewed
Hidenobu Yaku , Yoshio Yoshida, Hidehiko Okazawa, Yasushi Kiyono, Yuko Fujita, Daisuke Miyoshi
Anal. Chem. 89 ( 13 ) 6948 - 6953 2017.5
Joint Work
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Cell and Molecular Mechanics in Health and Disease Invited Reviewed
BioMed Research International Article ID 2860241 2017.2
Joint Work
DOI: 10.1155/2017/2860241
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Unexpected Position-Dependent Effects of Ribose G‑Quartets in G‑Quadruplexes Reviewed
J. Zhou, S. Amrane, F. Rosu, G.F. Salgado, Y. Bian, H. Tateishi-Karimata, E. Largy, D. N. Korkut, A. Bourdoncle, D. Miyoshi, J. Zhang, H. Ju, W. Wang, N. Sugimoto, V. Gabelica, and J. Mergny
J. Am. Chem. Soc. 139 7768 - 7779 2017
Joint Work
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Selective and Robust Stabilization of Triplex DNA Structures Using Cationic Comb-type Copolymers. Reviewed
Yamayoshi A, Miyoshi D, Zouzumi YK, Matsuyama Y, Ariyoshi J, Shimada N, Murakami A, Wada T, Maruyama A
J Phys Chem B 121 ( 16 ) 4015 - 4022 2017
Joint Work
Authorship:Lead author
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Reevaluation of the stability of G-quadruplex structures under crowding conditions Reviewed
Jun Zhou, Hisae Tateishi-Karimata, Jean-Louis Mergny, Mingpan Cheng, Zhaochi Feng, Daisuke Miyoshi, Naoki Sugimoto, Can Li
Biochimie 121 204 - 208 2016
Joint Work
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A reversible B-A transition of DNA duplexes induced by synthetic cationic copolymers Reviewed
Nonoka Yamaguchi, Yu-ki Zouzumi, Naohiko Shimada, Shuichi Nakano, Naoki Sugimoto, Atsushi Maruyama, Daisuke Miyoshi
Chem. Commun. 52 7446 - 7449 2016
Joint Work
Authorship:Lead author
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DNA structures under molecular crowding conditions with a phosphorylcholine derivative (MPC) Reviewed
Yu-mi Ueda, Tomohiro Konno, Kazuhiko Ishihara, Naoki Sugimoto, Daisuke Miyoshi
Transact. Mat. Res. Soc. Japan 40 99 - 102 2015
Joint Work
Authorship:Lead author
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DNA G-quadruplex detection system employing a protein fibril ligand Invited Reviewed
Ryuichi Maeda, Hidenobu Yaku, Takakazu Nakabayashi, Takashi Murashima, Naoki Sugimoto, Daisuke Miyoshi
Telomere and Telomerase 2 e691 2015
Joint Work
Authorship:Lead author
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A mRNA-responsive G-quadruplex-based drug release system Invited Reviewed
Hidenobu Yaku, Takashi Murashima, Daisuke Miyoshi, and Naoki Sugimoto
Sensors 15 ( 4 ) 9388 - 9403 2015
Joint Work
Authorship:Lead author
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Effects of background anionic compounds on the activity of the hammerhead ribozyme in Mg2+-unsaturated solutions Reviewed
Shu-ichi Nakano, Yuichi Kitagawa, Daisuke Miyoshi, Naoki Sugimoto
J. Biol. Inorg. Chem. 20 1049 - 1058 2015
Joint Work