Papers - NAGAHAMA Koji
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Tendon Tissue Regeneration With Cell Orientation Using an Injectable Alginate-Cell Cross-linked Gel Reviewed
Jun Yamaguchi, Kentaro Homan, Tomohiro Onodera, Masatake Matsuoka, Shoutaro Arakawa, Natsumi Ueda, Nana Kawate, Takayuki Nonoyama, Yoshinori Katsuyama, Koji Nagahama, Mitsuru Saito, Norimasa Iwasaki
The American Journal of Sports Medicine 2025.3
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Thixotropic β-Chitin Nanofiber Hydrogel with a Living Body-Responsive Self-Hardening Property and Its Application as a Sprayable Antiadhesion Barrier Reviewed International journal
Koji Nagahama, Kaho Tobiishi, Natsumi Ueda, Tatsuya Dode, Shahidul Islam Sobuj, Fumiya Yuasa, Kazuhiko Yamashita, Takahito Nishikata
ACS Applied Bio Materials 6 ( 7 ) 2636 - 2643 2023.7
Authorship:Lead author, Corresponding author
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Covalent Stem Cell-Combining Injectable Materials with Enhanced Stemness and Controlled Differentiation In Vivo Reviewed
Natsumi Ueda, Shiho Sawada, Fumiya Yuasa, Karen Kato, Koji Nagahama
ACS Applied Materials & Interfaces 14 ( 47 ) 52618 - 52633 2022.11
Authorship:Last author, Corresponding author
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Two-Dimensional Metal–Organic Framework-Based Cellular Scaffolds with High Protein Adsorption, Retention, and Replenishment Capabilities Reviewed
Tokitaka Katayama, Shintaro Tanaka, Takaaki Tsuruoka, and Koji Nagahama
ACS Applied Materials & Interfaces 14 ( 30 ) 34443 - 34454 2022.8
Authorship:Last author, Corresponding author
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Exportin-inspired artificial cell nuclear-exporting nanosystems Reviewed
Mitsuo Inui , Yuta Hamada , Nana Sejima , Natsumi Ueda , Tokitaka Katayama , Kimika Ono, Koji Nagahama
Nanoscale Advances 4 2637 - 2641 2022.5
Authorship:Last author, Corresponding author
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Kimika Ono, Manami Sumiya, Naohiro Yoshinobu, Tatsuya Dode, Tokitaka Katayama, Natsumi Ueda, Koji Nagahama
ACS Applied Bio Materials 5 ( 2 ) 471 - 482 2022.2
Authorship:Last author, Corresponding author
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Injectable Biocatalytic Nanocomposite Hydrogel Factories for Focal Enzyme-Prodrug Cancer Therapy Reviewed
Kimika Ono, Hiroyuki Hashimoto, Tokitaka Katayama, Natsumi Ueda, Koji Nagahama
Biomacromolecules 22 ( 10 ) 4217 - 4227 2021.10
Authorship:Last author, Corresponding author
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Koji Nagahama, Seika Aoyama, Natsumi Ueda, Yuka Kimura, Tokitaka Katayama, Kimika Ono
ACS Macro Letters 10 ( 8 ) 1073 - 1079 2021.8
Authorship:Lead author, Corresponding author
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Covalent cell-loading injectable hydrogel scaffold significantly promotes tissue regeneration in vivo compared with a conventional physical cell-loading hydrogel scaffold Reviewed
Yuka Kimura, Seika Aoyama, Natsumi Ueda, Tokitaka Katayama, Kimika Ono, Koji Nagahama
Advanced Biology 5 2000106 2021.2
Joint Work
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Bioinspired cell nuclear nanotransporters generated by self‐assembly of amphiphilic polysaccharide‐amino acid derivatives conjugates Reviewed
Koji Nagahama, Yoshinori Sano, Mitsuo Inui, Seika Aoyama, Tokitaka Katayama, Kimika Ono
Advanced Biosystems 4 1900189 2020
Joint Work
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美容医療 new horizon -幹細胞への期待- Invited Reviewed
市橋正光、長濱宏治
日本香粧品学会誌 44 30 - 35 2020
Joint Work
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細胞移植用インジェクタブルゲルの開発 Invited Reviewed
長濱宏治
Precision Medicine 3 724 - 728 2020
Single Work
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A thin hydrogel barrier linked onto cell surface sialic acids through covalent bonds induces cancer cell death in vivo Reviewed
Kimika Ono, Yuka Sanada, Yuka Kimura, Seika Aoyama, Natsumi Ueda, Tokitaka Katayama, Koji Nagahama
Biomaterials Science 8 577 - 585 2020
Joint Work
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細胞移植用スマートゲルの開発 Invited
長濱宏治、小野公佳、木村友香、青山青海
ケミカルエンジニヤリング 64 17 - 26 2019
Joint Work
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Living functional hydrogels generated by bioorthogonal cross-linking reactions of azide-modified cells with alkyne-modified polymers Reviewed
K. Nagahama, Y. Kimura, A. Takemoto
Nature Communications ( 9 ) 2195 2018.6
Joint Work
Authorship:Lead author
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Nanocomposite injectable gels capable of self-replenishing regenerative extracellular microenvironments for in vivo tissue engineering Reviewed
K. Nagahama, N. Oyama, K. Ono, A. Hotta, K. Kawauchi, T. Nishikata
Biomaterials Science ( 6 ) 550 - 561 2018.2
Joint Work
Authorship:Lead author
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Quantitative relationship between chemical properties and bioactivities of anti-microRNA oligonucleotides targeted to tumor-associated microRNA-21 Reviewed
Koji Nagahama, Kenta Iseda, Daichi Kawano, Junji Kawakami
Biochimie 137 124 - 131 2017.6
Joint Work
Authorship:Lead author
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PEG-based nanocomposite hydrogel: Thermoresponsive sol-gel transition controlled by PLGA-PEG-PLGA molecular weight and solute concentration Reviewed
Makoto Miyazaki, Tomoki Maeda, Kenji Hirashima, Naruki Kurokawa, Koji Nagahama, Atsushi Hotta
Polymer 115 246 - 254 2017.4
Joint Work
Authorship:Lead author
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細胞核DDSのためのナノトランスポーターの設計 Invited Reviewed
長濱宏治
Drug Delivery System 31 482 - 483 2016.11
Single Work
Authorship:Lead author
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Curcumisome nanovesicles generated by self-assembly of curcumin amphiphiles toward cancer theranostics Reviewed
K. Nagahama, T. Utsumi, T. Kumano, S. Maekawa, N. Oyama, J. Kawakami
Scientific Reports 6 30962 2016.8
Joint Work
Authorship:Lead author
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Enhanced Immunostimulating Activity of Lactobacilli-Mimicking Materials by Controlling Size Reviewed
Koji Nagahama, Takayuki Kumano, Yuichi Nakagawa, Naho Oyama, Hirokazu Tsuji, Kaoru Moriyama, Kan Shida, Koji Nomoto, Katsuyoshi Chiba, Kazuya Koumoto, and Jun Matsui
Bioconjugate Chemistry 26 1775 - 1781 2015.8
Joint Work
Authorship:Lead author
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生命分子-合成高分子ハイブリッドの開発とナノバイオマテリアル,その可能性 Invited
長濱宏治
Materials Stage 7 18 - 21 2015.7
Single Work
Authorship:Lead author
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Anticancer drug-based multifunctional nanogels through self-assembly of dextran-curcumin conjugates toward cancer theranostics Reviewed
Koji Nagahama, Yoshinori Sano, Takayuki Kumano
Bioorganic & Medical Chemistry Letters 25 2519 - 2522 2015.6
Joint Work
Authorship:Lead author
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Self-Assembling Polymer Micelle/Clay Nanodisk/Doxorubicin Hybrid Injectable Gels for Safe and Efficient Focal Treatment of Cancer Reviewed
Koji Nagahama, Daichi Kawano, Naho Oyama, Ayaka Takemoto, Takayuki Kumano, Junji Kawakami
Biomacromolecules 16 880 - 889 2015.3
Joint Work
Authorship:Lead author
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Synthesis and Immunestimulating Activity of Lactobacilli-Originated Polysaccharide-Polymeric Microparticle Conjugates Reviewed
Koji Nagahama, Takayuki Kumano, Tsubasa Nakata, Hirokazu Tsuji, Kaoru Moriyama, Kan Shida, Koji Nomoto, Katsuyoshi Chiba, Kazuya Koumoto, and Jun Matsui
Langmuir 31 1489 - 1495 2015.1
Joint Work
Authorship:Lead author
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A nanocomposite approach to develop biodegradable thermogels exhibiting excellent cell-compatibility for injectable cell delivery Reviewed
N. Oyama, H. Minami, D. Kawano, M. Miyazaki, T. Maeda, K. Toma, A. Hotta, K. Nagahama
Biomaterials Science 2 ( 8 ) 1057 - 1062 2014.6
Joint Work
Authorship:Lead author
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Biodegradable polymers exhibiting temperature-responsive sol-gel transition as injectable biomedical materials Reviewed
Koji Nagahama, Akihiro Takahashi, Yuichi Ohya
Reactive and Functional Polymers ( 73 ) 979 - 985 2013.5
Joint Work
Authorship:Lead author
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Enhanced stereocomplex formation of enantiomeric polylactides grafted on a polyrotaxane platform Reviewed
Koji Nagahama, Rie Aoki, Toshifumi Saito, Tatsuro Ouchi, Yuichi Ohya and Nobuhiko Yui
Polymer Chemistry ( 4 ) 1769 - 1773 2013.3
Joint Work
Authorship:Lead author
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Design of Biodegradable Injectable Polymers Exhibiting Temperature-Responsive Sol-Gel Transition Reviewed
Y. Ohya, H. Suzuki, K. Nagahama, A. Takahashi, T. Ouchi, A. Kuzuya
Advances in Science and Technology ( 86 ) 9 - 16 2013.3
Joint Work
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Biodegradable Stereocomplex Materials of Polylactide-grafted Dextran Exhibiting Soft and Tough Properties in Dry and Wet States Reviewed
K. Nagahama, K. Shimizu, S. Ichimura, A. Takahashi, T. Ouchi, Y. Ohya
Journal of Polymer Science Part A: Polymer Chemistry ( 50 ) 2669 - 2676 2012.5
Joint Work
Authorship:Lead author
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Biodegradable Polymeric Assemblies for Biomedical Materials Invited Reviewed
Y. Ohya, A. Takahashi, K. Nagahama
Advances in Polymer Science ( 247 ) 65 - 114 2012.4
Joint Work
Authorship:Lead author
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Biodegradable Nano-aggregates of Star-Shaped 8-arm PEG-PLLA Block Co-polymers for Encapsulation of Water-Soluble Macromolecules Reviewed
K. Nagahama, T. Saito, T. Ouchi, Y. Ohya
Journal of Biomaterials Science, Polymer Edition 22 407 2011.1
Joint Work
Authorship:Lead author
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“生きたバイオマテリアル”としての機能性細胞 Invited Reviewed
長濱宏治
バイオマテリアル 28 193 2010.8
Single Work
Authorship:Lead author
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Preparation of Nanoaggregates through Self-assembly of Amphiphilic Polyrotaxane Composed of PLLA–PEG–PLLA Triblock Copolymer and α-Cyclodextrins Reviewed
Koji Nagahama, Junpei Ohmura, Hiromi Sakaue, Tatsuro Ouchi, Yuichi Ohya and Nobuhiko Yui
Chemistry Letters 39 250 2010.4
Joint Work
Authorship:Lead author
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Biodegradable poly(l-lactide)-grafted α-cyclodextrin copolymer displaying specific dye absorption by host-guest interact Reviewed
Koji Nagahama, Keiko Shimizu, Tatsuro Ouchi, Yuichi Ohya
Reactive and Functional Polymers 69 891 2009.10
Joint Work
Authorship:Lead author
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Thermo-Sensitive Sol-Gel Transition of Poly(depsipeptide-co-lactide)-g-PEG Copolymers in Aqueous Solution Reviewed
Koji Nagahama, Yuichiro Imai, Teppei Nakayama, Junpei Ohmura, Tatsuro Ouchi, Yuichi Ohya
Polymer 50 3547 2009.10
Joint Work
Authorship:Lead author
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Polyrotaxane Composed of Poly-L-Lactide and α-Cyclodextrin Exhibiting Protease-Triggered Hydrolysis Reviewed
Yuichi Ohya, Seigo Takamido, Koji Nagahama, Tatsuro Ouchi, Ryo Katoono, Nobuhiko Yui
Biomacromolecules 10 2261 2009.10
Joint Work
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Hydrophobically Modified Biodegradable Poly(ethylene glycol) Copolymers that Form Temperature-Responsive Nanogels Reviewed
Koji Nagahama, Mihoko Hashizume, Hidetoshi Yamamoto, Tatsuro Ouchi, Yuichi Ohya
Langmuir 25 9734 2009.8
Joint Work
Authorship:Lead author
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Biodegradable Shape-Memory Polymers Exhibiting Sharp Thermal Transitions and Controlled Drug Release Reviewed
Koji Nagahama, Yuichi Ueda, Tatsuro Ouchi, Yuichi Ohya
Biomacromolecules 10 1789 2009.8
Joint Work
Authorship:Lead author
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Nuclease Resistant Methylphosphonate-DNA/LNA Chimeric Oligonucleotides Reviewed
Koji Nagahama, Rakesh Veedu, Jesper Wengel
Bioorganic and Medicinal Chemistry Letters 19 2707 2009.3
Joint Work
Authorship:Lead author
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Effects of Polydepsipeptide Side-Chain Groups on the Temperature Sensitivity of Triblock Copolymers Composed of Polydepsipeptides and Poly(ethylene glycol) Reviewed
Yuichi Ohya, Hidetoshi Yamamoto, Koji Nagahama, Tatsuro Ouchi
Journal of Polymer Science, Part A: Polymer Chemistry 47 3892 2009.2
Joint Work
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Temperature-Induced Hydrogel through Self-Assembly of Cholesterol-substituted Star PEG-b-PLLA Copolymers as an Injectable Scaffold for Tissue Engineering Reviewed
K. Nagahama, T. Ouchi, Y. Ohya,
Adv. Funct. Mater. 18 ( 8 ) 1220 - 1231 2008.11
Joint Work
Authorship:Lead author
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Biodegradable Nanogels Prepared by Self-Assembly of Poly(L-Lactide)-Grafted Dextran: Entrapment and Release of Protein Reviewed
K. Nagahama, T. Ouchi, Y. Ohya,
Macromol. Biosci. 8 ( 11 ) 1044 - 1952 2008.11
Joint Work
Authorship:Lead author
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Irreversible Temperature-Responsive Formation of High-strength Hydrogel from an Enantiomeric Mixture of Starburst Triblock Copolymers Consisting of 8-arm PEG and PLLA or PDLA Reviewed
K. Nagahama, K. Fujiura, S. Enami, T. Ouchi, Y. Ohya,
J. Polym. Sci. Part A Polym. Chem., 46 ( 18 ) 6317 - 6332 2008.11
Joint Work
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Design of Polylactide-Based Hydrogels as Biodegradable Soft-Biomaterials
Koji NAGAHAMA
2008.3
Single Work
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Impacts of Stereoregularity and Stereocomplex Formation on Physicochemical, Protein Adsorption and Cell Adhesion Behaviors of Star-Shaped 8-Arms Poly(ethylene glycol)-Poly(lactide) Block Copolymer Films Reviewed
K. Nagahama, Y. Nishimura, Y. Ohya,
Polymer, 48 ( 9 ) 2649 - 2658 2007.11
Joint Work
Authorship:Lead author
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Exhibition of Soft and Tenacious Characters Based on Liquid Crystal Formation by Introduction of Cholesterol Groups on Biodegradable Lactide Copolymer Reviewed
K. Nagahama, Y. Ueda, T. Ouchi, Y. Ohya
Biomacromolecules, 8 ( 12 ) 3938 - 3943 2007.11
Joint Work
Authorship:Lead author
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Molecular “Screw and Nut”: α-Cyclodextrin Recognizes Polylactide Chirality Reviewed
Y. Ohya, S. Takamido, K. Nagahama, T. Ouchi, T. Ooya, R. Katoono, N. Yui
Macromolecules, 40 ( 18 ) 6441 - 6444 2007.11
Joint Work
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Biodegradable Nanogel Formation of Polylactide-Grafted Dextran Copolymer in Dilute Aqueous Solution and Enhancement of Its Stability by Stereocomplexation, Reviewed
K. Nagahama, Y. Mori Y. Ohya, T. Ouchi
Biomacromolecules 8 ( 7 ) 2135 - 2141 2007.11
Joint Work
Authorship:Lead author
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The Suppression of Cell and Platelet Adhesion to Star-Shaped Poly(ethylene glycol)-Poly(L-lacitde) Block Copolymer Film, Reviewed
K. Nagahama, Y. Ohya, T. Ouchi,
Macromol. Biosci. 6 ( 6 ) 412 - 419 2006.11
Joint Work
Authorship:Lead author
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Synthesis of Star-Shaped 8arms Poly(ethylene glycol)-Poly(L-lacitde) Block Copolymer and Physical Properties of Its Solution Cast Film as Soft Biomaterial Reviewed
K. Nagahama, Y. Ohya, T. Ouchi,
Polym. J., 38 ( 8 ) 852 - 860 2006.11
Joint Work
Authorship:Lead author