写真a

NAKANO Shuuichi

Position

Professor

Research Field

Biomolecular chemistry, Basic chemistry, Bio-related chemistry

Research Fields, Keywords

Nucleic acid, DNA, RNA, Ribozyme, Fatty acid binding protein, Peptide, Thermodynamics, Kinetics, Molecular crowding

Homepage URL

https://www.konan-u.ac.jp/hp/FIRST_bmflab/English_site.html

Graduating School 【 display / non-display

  •  
    -
    1994.03

    Konan University   Faculty of Science   Graduated

Graduate School 【 display / non-display

  •  
    -
    1999.03

    Konan University  Graduate School, Division of National Science and Technology  Doctor's Course  Completed

Studying abroad experiences 【 display / non-display

  • 1999.04
    -
    2001.03

    Penn State University, USA   Postdoctoral fellow

Campus Career 【 display / non-display

  • 2013.04
    -
    Now

    KONAN UNIVERSITYProfessor  

  • 2009.04
    -
    2013.03

    KONAN UNIVERSITYAssociate Professor  

  • 2004.04
    -
    2009.03

    KONAN UNIVERSITYFrontier Institute for Biomolecular Engineering Research   Lecturer  

  • 2001.04
    -
    2004.03

    KONAN UNIVERSITY

 

Research Career 【 display / non-display

  • Mechanisms for functionalization of RNA ribozymes

    (not selected)  

    Project Year: 2006.04  -   

  • Thermodynamic and kinetic analysis of DNA and RNA interactions

    (not selected)  

    Project Year: 2004.04  -   

Published Papers 【 display / non-display

  • Hydroxyl groups in cosolutes regulate the G-quadruplex topology of telomeric DNA

    H. Tateishi-Karimata, D. Banerjee, T. Ohyama, S. Matsumoto, D. Miyoshi, S. Nakano, and N. Sugimoto

    Biochem. Biophys. Res. Commun.   525   177 - 183   2020.02  [Refereed]

    Joint Work

    DOI

  • Bulky cations greatly increase the turnover of a native hammerhead ribozyme

    S. Nakano, H. Yamashita, K. Tanabe, N. Sugimoto

    RSC advances   9   35820 - 35824   2019.11  [Refereed]

    Single Work

  • Stabilization of DNA loop structures by large cations

    S. Nakano, T. Ayusawa, Y. Tanino, N. Sugimoto

    J. Phys. Chem. B   123   7687 - 7694   2019.08  [Refereed]

    Joint Work

  • Thermal stability and conformation of DNA and proteins under the confined condition in the matrix of hydrogels

    S. Nakano, D. Yamaguchi, and N. Sugimoto

    Mol. Biol. Rep.   45   403 - 411   2018.04

    Joint Work

    DOI

  • Modulation of the ribozyme and deoxyribozyme activities using tetraalkylammonium ions

    S. Nakano, T. Watabe, and N. Sugimoto

    ChemPhysChem   18 ( 24 ) 3614 - 3619   2017.12  [Refereed]

    Joint Work

    DOI

display all >>

Books etc 【 display / non-display

  • バイオチップ実用化ハンドブック

    杉本直己・中野修一 (Part: Joint Work ,  第一節 DNAチップの基礎 1 ハイブリダイゼーション )

    エヌティーエス  2010.04 ISBN: 978-4-86043-270-6

  • Bottom-up Nanofabrication: Supramolecules, Self-Assemblies, and Organized Films

    S. Nakano and N. Sugimoto (Part: Joint Work ,  Energy of nucleic acid self-assemblies: From sequence to function through structure )

    American Scientific Publishers  2009.01 ISBN: 1-58883-079-9

  • 11. デザイナブル核酸修飾核酸(共著)

    中野 修一 (Part: Other )

    先端生物医学研究・医療のため遺伝子導入テクノロジー「ウイルスを用いない遺伝子導入法の材料、技術、方法論の新たな展開」遺伝子医学MOOK5(メディカルドゥ)  2006

Review Papers (Misc) 【 display / non-display

  • How does intracellular environment affect oligonucleotides used for nucleic acid pharmaceuticals?

    Shu-ichi Nakano

      52 ( 5 ) 42 - 44   2020.05

    Introduction and explanation (commerce magazine)   Single Work

  • 分子夾雑環境が制御する核酸分子の機能

    中野修一、杉本直己

    化学と工業 ( 日本化学会 )  72 ( 5 ) 401 - 403   2019.05

    Introduction and explanation (international conference proceedings)   Joint Work

  • 化学ツールとしての分子クラウディング

    中野修一・杉本直己

    化学フロンティア22 生命現象を理解する分子ツール最前線〜イメージングから生体機能解析まで〜 ( 化学同人 )    145 - 153   2010.09

    Introduction and explanation (commerce magazine)   Joint Work

  • 生体シグナル解析用の機能性核酸センサーの定量的デザイン

    中野修一・杉本直己

    シングルセル解析の最前線 ( シーエムシー出版 )    9 - 16   2010.03

    Introduction and explanation (commerce magazine)   Joint Work

  • 第一節 DNAチップの基礎1 ハイブリダイゼーション

    杉本直己・中野修一

    バイオチップ実用化ハンドブック ( エヌティーエス )    13 - 19   2010.03

    Single Work

display all >>

Conference Activities & Talks 【 display / non-display

  • 細胞内分子環境がDNA四重鎖の形成に与える影響:モデル実験系による検討

    田辺和也、森田紗奈、橋本留奈、中野修一

    第42回日本分子生物学会年会   (福岡国際会議場)  2019.12  -  2019.12 

  • 細胞内分子環境が核酸の構造と機能に与える影響―モデル実験系を用いた解析

    中野修一  [Invited]

    新学術領域「分子夾雑の生命化学」第2回関東地区シンポジウム  (東京大学)  2019.10  -  2019.10 

  • Stabilization of Noncanonical DNA Structures in the Presence of Bulky Cations

    Shu-ichi Nakano, Masao Horita, Kazuya Tanabe, Ryuta Morimoto, Naoki Sugimoto

    Commemorative International Symposium of the Japan Society of Nucleic Acids Chemistry (CISNAC2019)  (Konan University)  2019.07  -  2019.07 

  • Effects of bulky cations on the thermal stability of DNA G-quadruplexes with a long loop

    K. Tanabe, S. Nakano

    Konan Research Summit  (甲南大学)  2018.12  -  2018.12 

  • Influence of intracellular conditions on DNA and RNA: Insights from model studies

    Shu-ichi Nakano

    Konan Research Summit   (甲南大学)  2018.12  -  2018.12 

display all >>

Grant-in-Aid for Scientific Research 【 display / non-display

  • Studies on the functional role of unpaired regions of nucleic acid structures and their effects of molecular crowding

    Grant-in-Aid for Scientific Research(C)

    Project Year: 2018.04  -  2021.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2015.10  -  2019.03 

  • Grant-in-Aid for Scientific Research(C)

    Project Year: 2012.04  -  2015.03 

  • Grant-in-Aid for Scientific Research(A)

    Project Year: 2010.04  -   

  • Grant-in-Aid for Young Scientists(B)

    Project Year: 2007.04  -  2009.03 

display all >>

 

Qualification acquired 【 display / non-display

  • Hazardous Material Handler (first kind)