Papers - KAWAUCHI Keiko
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Loss of p53 enhances catalytic activity of IKKbeta through O-linked beta-N-acetyl glucosamine modification.
Kawauchi K, Araki K, Tobiume K, Tanaka N
Proceedings of the National Academy of Sciences of the United States of America 106 ( 9 ) 3431 - 3436 2009.3
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IKK/NF-kappaB signaling pathway inhibits cell-cycle progression by a novel Rb-independent suppression system for E2F transcription factors. Reviewed
Araki K, Kawauchi K, Tanaka N
Oncogene 27 ( 43 ) 5696 - 5705 2008.9
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Activated p53 induces NF-kappaB DNA binding but suppresses its transcriptional activation.
Kawauchi K, Araki K, Tobiume K, Tanaka N
Biochemical and biophysical research communications 372 ( 1 ) 137 - 141 2008.7
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Cycloprodigiosin hydrochloride activates the Ras-PI3K-Akt pathway and suppresses protein synthesis inhibition-induced apoptosis in PC12 cells.
Kawauchi K, Tobiume K, Iwashita K, Inagaki H, Morikawa T, Shibukawa Y, Moriyama Y, Hirata H, Kamata H
Bioscience, biotechnology, and biochemistry 72 ( 6 ) 1564 - 1570 2008.6
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p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation.
Kawauchi K, Araki K, Tobiume K, Tanaka N
Nature cell biology 10 ( 5 ) 611 - 618 2008.5
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Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.
Abe Y, Oda-Sato E, Tobiume K, Kawauchi K, Taya Y, Okamoto K, Oren M, Tanaka N
Proceedings of the National Academy of Sciences of the United States of America 105 ( 12 ) 4838 - 4843 2008.3
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Suppression of AP-1 activity by cycloprodigiosin hydrochloride.
Kawauchi K, Tobiume K, Kaneko S, Kaneshiro K, Okamoto S, Ueda E, Kamata H, Moriyama Y, Hirata H
Biological & pharmaceutical bulletin 30 ( 9 ) 1792 - 1795 2007.9
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The negative regulation of p53 by hedgehog signaling Reviewed
Abe Yoshinori, Oda-Sato Eri, Tobiume Kei, Kawauchi Keiko, Okamoto Koji, Taya Yoichi, Tanaka Nobuyuki
CANCER RESEARCH 66 ( 8 ) 2006.4
Joint Work
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Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.
Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K
Biochemistry 44 ( 10 ) 3891 - 3898 2005.3
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Cycloprodigiosin up-regulates inducible nitric oxide synthase gene expression in hepatocytes stimulated by interleukin-1beta.
Teshima S, Nakanishi H, Kamata K, Kaibori M, Kwon AH, Kamiyama Y, Nishizawa M, Ito S, Okumura T
Nitric oxide : biology and chemistry 11 ( 1 ) 9 - 16 2004.8
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Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation.
Kyo S, Sada K, Qu X, Maeno K, Miah SM, Kawauchi-Kamata K, Yamamura H
Genes to cells : devoted to molecular & cellular mechanisms 8 ( 10 ) 825 - 836 2003.10
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Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.
Maeno K, Sada K, Kyo S, Miah SM, Kawauchi-Kamata K, Qu X, Shi Y, Yamamura H
The Journal of biological chemistry 278 ( 27 ) 24912 - 24920 2003.7
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Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops.
Kamata H, Manabe T, Oka Si, Kamata K, Hirata H
FEBS letters 519 ( 1-3 ) 231 - 237 2002.5
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Synergistic effects induced by cycloprodigiosin hydrochloride and epirubicin on human breast cancer cellsYamamoto D Reviewed
Tanaka K, Nakai K, Baden T, Inoue K, Yamamoto C, Takemoto H, Kamata K, Hirata H, Morikawa S, Inubushi T, Hioki K
Breast Cancer Research and Treatment 72 2002
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Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) alpha-induced transcriptional activation by NF-kappaB Reviewed
Kamata K, Okamoto S, Oka S, Kamata H, Yagisawa H, Hirata H
FEBS Letters 507 2001
Authorship:Lead author
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Cycloprodigiosin hydrochloride, a H+/Cl- symporter, induces apoptosis in human colon cancer cell lines in vitro
Yamamoto C, Takemoto H, Kuno K, Yamamoto D, Nakai K, Baden T, Kamata K, Hirata H, Watanabe T, Inoue K
Oncology Reports 8 2001
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Cycloprodigiosin hydrochloride, H(+)/CL(-) symporter, induces apoptosis and differentiation in HL-60 cells Reviewed
Yamamoto D, Uemura Y, Tanaka K, Nakai K, Yamamoto C, Takemoto H, Kamata K, Hirata H, Hioki K
International Journal of Cancer 88 2000
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N-acetylcysteine suppresses TNF-induced NF-kappaB activation through inhibition of IkappaB kinases Reviewed
Oka S, Kamata H, Kamata K, Yagisawa H, Hirata H
FEBS Letters 2000
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Demonstration of Cl- requirement for inhibition of vacuolar acidification by cycloprodigiosin in situ Reviewed
Nakayasu T, Kawauchi K, Hirata H, Shimmen T
Plant & Cell Physiol 41 2000
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Cycloprodigiosin hydrochloride, a new H(+)/Cl(-) symporter, induces apoptosis in human and rat hepatocellular cancer cell lines in vitro and inhibits the growth of hepatocellular carcinoma xenografts in nude mice Reviewed
Yamamoto C, Takemoto H, Kuno K, Yamamoto D, Tsubura A, Kamata K, Hirata H, Yamamoto A, Kano H, Seki T, Inoue K
Hepatology 1999