Papers - NISHIKATA Takahito
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Effects of platinum and palladium nanocolloid on macrophage polarization in relevance to repigmentation of vitiligo. Reviewed
Minamiyama Y, Ishikawa M, Shibata T, Tsuji G, Nishikata T, Takemura S, Ichihashi M.
J Cutan Immunol Allergy 1 139 - 146 2018.8
Joint Work
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Phagocytic activation of macrophages with serum MAF depends on engulfment efficiency and not migratory activity. Reviewed
Mashiba R, Ishikawa M, Sumiya YU, Kawakatsu K, Tran NK, Nishikata T.
Anticancer Res. 38 ( 7 ) 4295 - 4298 2018.7
Joint Work
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Nanocomposite injectable gels capable of self-replenishing regenerative extracellular microenvironments for in vivo tissue engineering Reviewed
K. Nagahama, N. Oyama, K. Ono, A. Hotta, K. Kawauchi, T. Nishikata
Biomater Sci. 6 ( 3 ) 550 - 561 2018.2
Joint Work
DOI： 10.1039/c7bm01167a.
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A high-throughput quantitative assay system for macrophage phagocytic activity. Reviewed
Mami Ishikawa, Riho Mashiba, Kumpei Kawakatsu, Ngoc Kiet Tran, Takahito Nishikata
macrophage 2018.2
Joint Work
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Microtubule array observed in the posterior-vegetal cortex during cytoplasmic and cortical reorganization of the ascidian egg. Reviewed
Hirokazu Ishii, Toshiyuki Goto and Takahito Nishikata
Growth and Differentiation 59 648 - 656 2017
Joint Work
DOI： 10.1111/dgd.12405
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Macrophages Exhibit a Large Repertoire of Activation States via Multiple Mechanisms of Macrophage-activating Factors. Reviewed
Sumiya Y.U., Inoue T., Ishikawa M., Inui T., Kuchiike D., Kubo K., Uto Y., Nishikata T.
Anticancer Res. 36 ( 7 ) 3619 - 3623 2016.7
Joint Work
Authorship：Lead author
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Case Report: GcMAF Treatment in a Patient with Multiple Sclerosis. Reviewed
Inui T., Katsuura G., Kubo K., Kuchiike D., Chenery L., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3771 - 3774 2016.7
Joint Work
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Case Report: A Non-small Cell Lung Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Tumor Treating Fields. Reviewed
Inui T., Amitani H., Kubo K., Kuchiike D., Uto Y., Nishikata T., Mette M.
Anticancer Res. 36 ( 7 ) 3767 - 6770 2016.7
Joint Work
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Establishment of a macrophage-activating factor (MAF) assay system using human-monocytic cell line, THP-1. Reviewed
Inoue T., Ishikawa M., Sumiya Y., Kohda H, Inui T., Kuchiike D., Kubo K., Uto Y and Nishikata T.
Anticancer Research 35 4441 - 4445 2015.8
Joint Work
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Oral Colostrum Macrophage-activating Factor for Serious Infection and Chronic Fatigue Syndrome: Three Case Reports. Reviewed
Inui T., Kubo K., Kuchiike D., Uto Y., Nishikata T., Sakamoto N., Mette M.
Anticancer Research 35 ( 8 ) 4545 - 4549 2015.8
Joint Work
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Macrophage Activation Mechanisms in Human Monocytic Cell Line-derived Macrophages. Reviewed
Sumiya Y, Ishikawa M, Inoue T, Inui T, Kuchiike D, Kubo K, Uto Y, Nishikata T
Anticancer research 35 ( 8 ) 4447 - 4451 2015.8
Joint Work
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Establishment of a Macrophage-activating Factor Assay System Using the Human Monocytic Cell Line THP-1 Reviewed
Takahiro Inoue, Mami Ishikawa, Yu Sumiya, Haruka Kohda, Toshio Inui, Daisuke Kuchiike, Kentaro Kubo, Yoshihiro Uto, Takahito Nishikata
ANTICANCER RESEARCH 35 ( 8 ) 4441 - 4445 2015.8
Joint Work
Publisher：INT INST ANTICANCER RESEARCH
Background: As the mechanism of macrophage activation is not well-understood, standardization of an assay system for measuring phagocytic activities of macrophages will be useful for research on macrophages. Previously, we established a novel standardized macrophage-activating factor (MAF) assay system using U937. Materials and Methods: Using the human monocytic cell line THP-1, another standardized MAF assay system was established. Characteristic gene expression of U937- and THP-1-derived macrophages was compared by gene expression microarray analysis. Results: Both U937- and THP-1-derived macrophages showed obvious phagocytic activities with unique characteristics and, therefore, could not be assigned to a single sub-type. Conclusion: Activation of macrophages is an intricate cellular process. Comparison of our two novel assay systems provides new insights into macrophage activation mechanisms.
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Effects of four-week feed restriction on toxicological parameters in beagle dogs. Reviewed
Takamatsu K., Yamashita H., Satake S., Kazusa K., Tabata H., and Nishikata T.
Experimental Animals 64 269 - 280 2015.5
Joint Work
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Refinement and verification of test conditions for colony-forming unit assay in dog bone marrow cells with preservable colony specimens. Reviewed
Takamatsu K., Wakata A., Hirota R., Tabata H., and Nishikata T.
Comparative Clinical Pathology 23 ( 5 ) 1133 - 1139 2014.9
Joint Work
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Case Report: A Breast Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Hormone Therapy. Reviewed
Inui T, Makita K, Miura H, Matsuda A. Kuchiike D, Kubo K, Mette M, Uto Y, Nishikata T, Hori H, and Sakamoto N.
Anticancer Research 34 ( 8 ) 4589 - 4593 2014.8
Joint Work
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Refinement and verification of test conditions for colony-forming unit assay in rat bone marrow cells with preservable colony specimens Reviewed
Takamatsu K., Wakata A., Tabata H., and Nishikata T.
Comparative Clinical Pathology 23 ( 3 ) 569 - 575 2014.5
Joint Work
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Mitochondrial inhibitor sodium azide inhibits the reorganization of mitochondria-rich cytoplasm and the establishment of the anteroposterior axis in ascidian embryo Reviewed
Ishii H., Shirai T., Makino C. and Nishikata T
Devl. Growth Differ. 56 175 - 188 2014
Joint Work
DOI： 10.1111/dgd.12117
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A Novel Assay System for Macrophage Activating Factor Activity Using a Human U937 Cell Line. Reviewed
Ishikawa M, Inoue T, Inui T, Kuchiike D, Kubo K, Uto Y, and Nishikata T,
Anticancer Research 34 ( 8 ) 4577 - 4581 2014
Joint Work
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Simultaneous Expression of Cancer Stem Cell-like Properties and Cancer-associated Fibroblast-like Properties in a Primary Culture of Breast Cancer Cells Reviewed
Ishikawa M, Inoue T, Shirai T, Takamatsu K, Kunihiro S, Ishii H, and Nishikata T
Cancers 6 1570 - 1578 2014
Joint Work
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Biochemical purification of mitochondrial HSP60 and ATPsynthase from ascidian eggs: Implications for antibody specificity Reviewed
Janet Chenevert, Gerard Pruliere, Hirokazu Ishii, Christian Sardet, Takahito Nishikata
PLoS One 8 ( 1 ) e52996 2013.1
Joint Work